Phenanthridine, 4-methyl-6-phenyl-

Base Information

• Chemical Name: Phenanthridine, 4-methyl-6-phenyl-
• CAS No.: 112421-99-5
• Molecular Formula: C20H15N
• Molecular Weight: 269.34000
• Mol file: 112421-99-5.mol

Synonyms:

Chemical Property of Phenanthridine, 4-methyl-6-phenyl-

Chemical Property:

• Melting Point: 114.5-115.5 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 443.5±14.0 °C(Predicted)
• PSA: 12.89000
• Density: 1.158±0.06 g/cm3(Predicted)
• LogP: 5.36340

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phenanthridine, 4-methyl-6-phenyl-

There total 14 articles about Phenanthridine, 4-methyl-6-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

N-(2-methyl-6-phenylphenyl)benzamide (112421-98-4) → 4-methyl-6-phenylphenanthridine (112421-99-5)

Guidance literature:

With PPA; at 150 ℃; for 0.25h;

DOI:10.1021/jm00399a015

Reference yield: 79.0%

iodobenzene (591-50-4) + 2-isocyano-3-methyl-1,1’-biphenyl → 4-methyl-6-phenylphenanthridine (112421-99-5)

Guidance literature:

iodobenzene; With palladium diacetate; potassium carbonate; triphenylphosphine; Trimethylacetic acid; In toluene; at 100 ℃; for 0.5h; Schlenk technique; Inert atmosphere;

2-isocyano-3-methyl-1,1’-biphenyl; In toluene; for 1h; Schlenk technique; Inert atmosphere;

DOI:10.1021/jo502731n

Reference yield: 78.0%

C20H17N → 4-methyl-6-phenylphenanthridine (112421-99-5)

Guidance literature:

With iodine; potassium carbonate; In tetrahydrofuran; methanol; at 60 ℃; for 2h;

DOI:10.1002/ejoc.201901278

upstream raw materials:

N-(2-methyl-6-phenylphenyl)benzamide

3-methyl-2-nitroaniline

3-methyl-[1,1'-biphenyl]-2-amine

benzoyl chloride

Downstream raw materials:

6-Phenyl-phenanthridine-4-carboxylic acid (2-dimethylamino-ethyl)-amide

6-Phenyl-phenanthridine-4-carboxylic acid (3-dimethylamino-propyl)-amide; hydrochloride

6-Phenyl-phenanthridine-4-carboxylic acid (4-dimethylamino-butyl)-amide; hydrochloride

6-phenylphenanthridine-4-carboxylic acid