Guanidine, N,N-dimethyl-N',N''-bis(4-methylphenyl)-

Base Information

• Chemical Name: Guanidine, N,N-dimethyl-N',N''-bis(4-methylphenyl)-
• CAS No.: 112463-60-2
• Molecular Formula: C₁₇H₂₁N₃
• Molecular Weight: 267.374
• Mol file: 112463-60-2.mol

Synonyms:

Chemical Property of Guanidine, N,N-dimethyl-N',N''-bis(4-methylphenyl)-

Chemical Property:

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Guanidine, N,N-dimethyl-N',N''-bis(4-methylphenyl)-

There total 2 articles about Guanidine, N,N-dimethyl-N',N''-bis(4-methylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N-dimethyl-N′,N″-bis(4-methylphenyl)guanidinium iodide (1085473-89-7) → N,N-dimethyl-N′,N″-bis(4-methylphenyl)guanidine (112463-60-2)

Guidance literature:

With sodium carbonate; In diethyl ether; water; Saturated solution;

DOI:10.1021/ic302570s

Reference yield:

N,N'-Bis(p-tolyl)thiourea (621-01-2) → N,N-dimethyl-N′,N″-bis(4-methylphenyl)guanidine (112463-60-2)

Guidance literature:

Multi-step reaction with 3 steps

1: methanol / 2 h / Reflux

2: methanol; ethanol / 7 h / 70 °C / Sealed tube

3: sodium carbonate / diethyl ether; water / Saturated solution

With sodium carbonate; In methanol; diethyl ether; ethanol; water;

DOI:10.1021/ic302570s

Reference yield:

bis(1,5-cyclooctadiene)diiridium(I) dichloride (12112-67-3) + (C6H4CH3N)2(CH3)2NCH (112463-60-2) → (1,5-cyclooctadiene)(N,N-dimethyl-N′,N″-bis(4-methylphenyl)guanidinato)iridium(I) (1085473-86-4)

Guidance literature:

With methyllithium; In not given; byproducts: LiCl; under inert atm. treatment of guanidine with MeLi and subsequent react. with Ir complex;

DOI:10.1021/ic801867r

upstream raw materials:

N,N-dimethyl-N′,N″-bis(4-methylphenyl)guanidinium iodide

N,N'-Bis(p-tolyl)thiourea

Downstream raw materials:

(1,5-cyclooctadiene)(N,N-dimethyl-N′,N″-bis(4-methylphenyl)guanidinato)iridium(I)

Refernces