Methanesulfonic acid, trifluoro-, 2-(hydroxymethyl)phenyl ester

Base Information

Chemical Name:Methanesulfonic acid, trifluoro-, 2-(hydroxymethyl)phenyl ester
CAS No.:112533-09-2
Molecular Formula:C8H7F3O4S
Molecular Weight:256.202
Hs Code.:
DSSTox Substance ID:DTXSID80450564
Nikkaji Number:J514.121D
Wikidata:Q82270348

Synonyms:112533-09-2;Methanesulfonic acid, trifluoro-, 2-(hydroxymethyl)phenyl ester;DTXSID80450564;Trifluoromethanesulfonic acid 2-hydroxymethylphenyl ester

Suppliers and Price of Methanesulfonic acid, trifluoro-, 2-(hydroxymethyl)phenyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Methanesulfonic acid, trifluoro-, 2-(hydroxymethyl)phenyl ester

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:256.00171436
Heavy Atom Count:16
Complexity:319

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)CO)OS(=O)(=O)C(F)(F)F

Technology Process of Methanesulfonic acid, trifluoro-, 2-(hydroxymethyl)phenyl ester

There total 3 articles about Methanesulfonic acid, trifluoro-, 2-(hydroxymethyl)phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 84761-77-3
2-formylphenyl triflate

: 112533-09-2
2-<<(Trifluoromethyl)sulfonyl>oxy>benzyl alcohol

Guidance literature:: With sodium tetrahydroborate; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1021/acs.orglett.8b00196

Reference yield: 92.0%

: 17763-70-1
methyl 2-(trifluoromethylsulfonyloxy)benzoate

: 112533-09-2
2-<<(Trifluoromethyl)sulfonyl>oxy>benzyl alcohol

Guidance literature:: With diisobutylaluminium hydride; In hexane; dichloromethane; -78 deg C, 30 min then 23 deg C, 30 min;
DOI:10.1021/ja00213a032

Reference yield:

: 90-02-8
salicylaldehyde

: 112533-09-2
2-<<(Trifluoromethyl)sulfonyl>oxy>benzyl alcohol

Guidance literature:: Multi-step reaction with 2 steps

1: dichloromethane / 3 h / 20 °C

2: sodium tetrahydroborate / methanol / 20 °C

With sodium tetrahydroborate; In methanol; dichloromethane;
DOI:10.1021/jo402626u