Bulleyaconitine A

Base Information

• Chemical Name: Bulleyaconitine A
• CAS No.: 107668-79-1
• Molecular Formula: C35H49NO9
• Molecular Weight: 627.76
• Mol file: 107668-79-1.mol

Synonyms:2H-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine,methanone deriv.;Aconitane, methanone deriv.;

Chemical Property of Bulleyaconitine A

Chemical Property:

• Vapor Pressure: 4.82E-20mmHg at 25°C
• Refractive Index: 1.589
• Boiling Point: 690.9 °C at 760 mmHg
• PKA: 13.12±0.70(Predicted)
• Flash Point: 371.7 °C
• PSA: 112.99000
• Density: 1.28 g/cm³
• LogP: 2.92650

Purity/Quality:

≥98% ^*data from raw suppliers

Bulleyaconitine A ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: Bulleyaconitine A is an aconitine-type two terpene alkaloid, and its molecular formula is C35H49NO10.?As early as 1980, bulleyaconitine was separated and extracted from a traditional analgesic and anti-inflammatory herb in the west of Yunnan called dianxi dula (or dianxi wutou) (Aconitum bulleyanum Diels), by the Kunming Institute of Botany, Chinese Academy of Sciences . At present, bulleyaconitine A can be separated from Aconitum plants, for example, dianxi wutou (Aconitum bulleyanum Diels), cujing wutou (Aconitum crassicaule W.T.?Wang), changhui wutou (Aconitum georgei Comber), and zhiyuan wutou (Aconitum transsectum Diels).
• Physical properties: Appearance: white powder. Solubility: soluble in methanol, ethanol, chloroform, and ether; insoluble in water; and easily dissolved in dilute hydrochloric acid or dilute sulfuric acid . Melting point: 160–165?°C
• Clinical Use: 1. Rheumatic immune disease. Since listing, bulleyaconitine A has been applied in clinical treatment for rheumatoid arthritis and osteoarthritis, receiving good curative effects.2. Chronic pain. Bulleyaconitine A does not belong to NSAID, and it exerts its effects by regulating the sodium ion channel. So there is little psychological dependence and organ toxicity, avoiding gastrointestinal/cardiovascular/renal adverse reactions and drug dependence or other potential dangers caused by NSAID and opioid analgesics.