Fertirelin

Base Information

• Chemical Name: Fertirelin
• CAS No.: 38234-21-8
• Molecular Formula: C55H76N16O12
• Molecular Weight: 1153.29
• Mol file: 38234-21-8.mol

Synonyms:9-(N-Ethyl-L-prolinamide)-10-deglycinamide; Luteinizing hormone releasing factor;1-9-Luteinizinghormone-releasing factor (swine), 9-(N-ethyl-L-prolinamide)-;

Chemical Property of Fertirelin

Chemical Property:

• Refractive Index: 1.698
• PKA: 9.82±0.15(Predicted)
• PSA: 429.04000
• Density: 1.49 g/cm³
• LogP: 1.94170
• Storage Temp.: -15°C
• Solubility.: DMSO (Slightly), Water (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

Fertirelin 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 60
• Safety Statements: 53-22-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Fertirelin Acetate is a gonadotropin-releasing hormone (GnRH) agonists that induces estrus in dogs and cats . It also has an effect on the pregnancy rate in cows.

Technology Process of Fertirelin

There total 2 articles about Fertirelin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pGlu-His(Trt)-Trp-Ser(tBu)-Tyr(tBu)-Gly-Leu-Arg(Pbf)-Pro-NHEt → fertirelin (38234-21-8)

Guidance literature:

With chlorotriisopropylsilane; ethane-1,2-dithiol; trifluoroacetic acid; at 20 ℃; for 2h;

Reference yield:

→ fertirelin (38234-21-8)

Guidance literature:

Peptid I, HF;

DOI:10.1021/bi00699a015

Refernces

• 1、 Arnold,Flouret,Morgan,Rippel,White. "Synthesis and biological activity of some analogs of the gonadotropin releasing hormone". . p. 314 - 319,315, 316. Retrieved 2007/10/05.