5-[2-(Propylsulfanyl)phenyl]-1,3,4-thiadiazol-2-amine

Base Information

Chemical Name:5-[2-(Propylsulfanyl)phenyl]-1,3,4-thiadiazol-2-amine
CAS No.:112764-31-5
Molecular Formula:C₁₁H₁₃N₃S₂
Molecular Weight:251.376
Hs Code.:
DSSTox Substance ID:DTXSID701235235

Synonyms:112764-31-5;5-[2-(propylsulfanyl)phenyl]-1,3,4-thiadiazol-2-amine;DTXSID701235235;EN300-11961392;5-[2-(Propylthio)phenyl]-1,3,4-thiadiazol-2-amine;Z2181035010

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-[2-(Propylsulfanyl)phenyl]-1,3,4-thiadiazol-2-amine

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:251.05508977
Heavy Atom Count:16
Complexity:215

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCSC1=CC=CC=C1C2=NN=C(S2)N

Technology Process of 5-[2-(Propylsulfanyl)phenyl]-1,3,4-thiadiazol-2-amine

There total 1 articles about 5-[2-(Propylsulfanyl)phenyl]-1,3,4-thiadiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 112764-60-0
C₁₁H₁₅N₃OS₂

: 112764-31-5
5-(2-Propylsulfanyl-phenyl)-[1,3,4]thiadiazol-2-ylamine

Guidance literature:: With PPA; at 100 ℃; for 1h;
DOI:10.1021/jm00400a003

Reference yield:

: 112764-31-5
5-(2-Propylsulfanyl-phenyl)-[1,3,4]thiadiazol-2-ylamine

: 112764-37-1
2-Chloro-5-[2-(propane-1-sulfinyl)-phenyl]-[1,3,4]thiadiazole

Guidance literature:: With hydrogenchloride; copper; acetic acid; sodium nitrite; at 15 - 20 ℃; for 4h;
DOI:10.1021/jm00400a003

Reference yield:

: 112764-31-5
5-(2-Propylsulfanyl-phenyl)-[1,3,4]thiadiazol-2-ylamine

: {5-[2-(Propane-1-sulfinyl)-phenyl]-[1,3,4]thiadiazol-2-yl}-hydrazine; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: conc. HCl, aq. NaNO₂, copper, glacial acetic acid / 4 h / 15 - 20 °C

2: 45 percent / 1.) hydrazine hydrate, 2.) HCl / ethanol / 4 h / Heating

With hydrogenchloride; copper; hydrazine hydrate; acetic acid; sodium nitrite; In ethanol;
DOI:10.1021/jm00400a003