Technology Process of Cyclohexaneacetic acid, 1-(nitromethyl)-, methyl ester
There total 1 articles about Cyclohexaneacetic acid, 1-(nitromethyl)-, methyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrabutyl ammonium fluoride;
In
tetrahydrofuran; toluene;
at 100 ℃;
for 5h;
under 6000.6 Torr;
Time;
Temperature;
DOI:10.1002/anie.201409765
- Guidance literature:
-
methyl 1-(nitromethyl)cyclohexyl-acetate;
With
potassium hydroxide; water;
In
methanol;
at 20 ℃;
for 24h;
With
potassium dihydrogenphosphate;
In
water;
pH=7;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: lithium hydroxide; water / toluene / 1 h / 50 °C / 3750.38 Torr
2: hydrogen; palladium 10% on activated carbon / methanol / 60 °C / 45004.5 Torr
With
palladium 10% on activated carbon; water; hydrogen; lithium hydroxide;
In
methanol; toluene;
DOI:10.1002/anie.201409765
