3-{[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]sulfanyl}-2H-1-benzopyran-2-one

Base Information

Chemical Name:3-{[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]sulfanyl}-2H-1-benzopyran-2-one
CAS No.:112779-56-3
Molecular Formula:C₁₉H₁₃NO₃S₂
Molecular Weight:367.449
Hs Code.:
DSSTox Substance ID:DTXSID00548790
Wikidata:Q82427622

Synonyms:112779-56-3;DTXSID00548790;3-{[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]sulfanyl}-2H-1-benzopyran-2-one

Suppliers and Price of 3-{[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]sulfanyl}-2H-1-benzopyran-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3-{[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]sulfanyl}-2H-1-benzopyran-2-one

Chemical Property:

XLogP3:5.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:367.03368562
Heavy Atom Count:25
Complexity:519

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=CSC(=N2)SC3=CC4=CC=CC=C4OC3=O

Technology Process of 3-{[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]sulfanyl}-2H-1-benzopyran-2-one

There total 5 articles about 3-{[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]sulfanyl}-2H-1-benzopyran-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 112779-62-1
[4-(4-Methoxy-phenyl)-thiazol-2-ylsulfanyl]-acetic acid [1-(2-hydroxy-phenyl)-meth-(E)-ylidene]-hydrazide

: 112779-56-3
3-<4'-(4''-methoxyphenyl)thiazol-2'-ylthio>-2H-1-benzopyran-2-one

Guidance literature:: With PPA; at 100 ℃; for 15h;
DOI:10.1016/S0040-4020(01)90053-5

Reference yield:

: 2104-05-4
2-mercapto-4-(4'-methoxyphenyl)thiazole

: 112779-56-3
3-<4'-(4''-methoxyphenyl)thiazol-2'-ylthio>-2H-1-benzopyran-2-one

Guidance literature:: Multi-step reaction with 4 steps

1: 97 percent / K₂CO₃

2: 85 percent / hydrazine

3: 96 percent / acetic acid / ethanol / 2 h / Heating

4: 40 percent / polyphosphoric acid / 15 h / 100 °C

With PPA; potassium carbonate; hydrazine; acetic acid; In ethanol;
DOI:10.1016/S0040-4020(01)90053-5

Reference yield:

: 112779-69-8
ethyl <4-(4'-methoxyphenyl)thiazol-2-ylthio>acetate

: 112779-56-3
3-<4'-(4''-methoxyphenyl)thiazol-2'-ylthio>-2H-1-benzopyran-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: 85 percent / hydrazine

2: 96 percent / acetic acid / ethanol / 2 h / Heating

3: 40 percent / polyphosphoric acid / 15 h / 100 °C

With PPA; hydrazine; acetic acid; In ethanol;
DOI:10.1016/S0040-4020(01)90053-5