3-cyclohexyl-4-hydroxy-1H-1,2,4-triazol-5(4H)-one

Base Information

Chemical Name:3-cyclohexyl-4-hydroxy-1H-1,2,4-triazol-5(4H)-one
CAS No.:112799-92-5
Molecular Formula:C8H13N3O2
Molecular Weight:183.21
Hs Code.:
DSSTox Substance ID:DTXSID40551602
Wikidata:Q82431355

Synonyms:112799-92-5;3-cyclohexyl-4-hydroxy-1H-1,2,4-triazol-5(4H)-one;DTXSID40551602;5-Cyclohexyl-4-hydroxy-2,4-dihydro-3H-1,2,4-triazol-3-one

Suppliers and Price of 3-cyclohexyl-4-hydroxy-1H-1,2,4-triazol-5(4H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 3-cyclohexyl-4-hydroxy-1H-1,2,4-triazol-5(4H)-one

Chemical Property:

XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:183.100776666
Heavy Atom Count:13
Complexity:246

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(CC1)C2=NNC(=O)N2O

Technology Process of 3-cyclohexyl-4-hydroxy-1H-1,2,4-triazol-5(4H)-one

There total 2 articles about 3-cyclohexyl-4-hydroxy-1H-1,2,4-triazol-5(4H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 112800-00-7
N'-Cyclohexanecarbonyl-hydrazinecarboxylic acid methyl ester

: 112799-92-5
3-Cyclohexyl-1H-1,2,4-triazolin-5-on

Guidance literature:: With sodium hydroxide; hydroxylamine hydrochloride; In methanol; water; for 72h; Ambient temperature;
DOI:10.1002/ardp.198700027

Reference yield:

: 2719-27-9
cyclohexanylcarbonyl chloride

: 112799-92-5
3-Cyclohexyl-1H-1,2,4-triazolin-5-on

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / Et₃N / CH₂Cl₂ / 5 h / Ambient temperature

2: 83 percent / NH₂OH*HCl, NaOH / methanol; H₂O / 72 h / Ambient temperature

With sodium hydroxide; hydroxylamine hydrochloride; triethylamine; In methanol; dichloromethane; water;
DOI:10.1002/ardp.198700027