N-Cyclohexyl-N'-(2-methyl-4-quinolinyl)-N''-2-pyridinylguanidine

Base Information

Chemical Name:N-Cyclohexyl-N'-(2-methyl-4-quinolinyl)-N''-2-pyridinylguanidine
CAS No.:71080-09-6
Molecular Formula:C₂₂H₂₅N₅
Molecular Weight:359.474
Hs Code.:
DSSTox Substance ID:DTXSID20991406
ChEMBL ID:CHEMBL60077

Synonyms:BRN 0449429;N-Cyclohexyl-N'-(2-methyl-4-quinolinyl)-N''-2-pyridinylguanidine;71080-09-6;Guanidine, 1-cyclohexyl-2-(2-methyl-4-quinolyl)-3-(2-pyridyl)-;Guanidine, N-cyclohexyl-N'-(2-methyl-4-quinolinyl)-N''-2-pyridinyl-;CHEMBL60077;DTXSID20991406;LS-73515;N''-Cyclohexyl-N-(2-methylquinolin-4(1H)-ylidene)-N'-pyridin-2-ylguanidine

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Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-Cyclohexyl-N'-(2-methyl-4-quinolinyl)-N''-2-pyridinylguanidine

Chemical Property:

Vapor Pressure:1.25E-11mmHg at 25°C
Boiling Point:537.7°Cat760mmHg
Flash Point:279°C
Density:1.21g/cm³
XLogP3:4.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:359.21099582
Heavy Atom Count:27
Complexity:487

Purity/Quality:

Safty Information:

Pictogram(s):
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MSDS Files:

Useful:

Canonical SMILES:CC1=NC2=CC=CC=C2C(=C1)NC(=NC3CCCCC3)NC4=CC=CC=N4

Technology Process of N-Cyclohexyl-N'-(2-methyl-4-quinolinyl)-N''-2-pyridinylguanidine

There total 3 articles about N-Cyclohexyl-N'-(2-methyl-4-quinolinyl)-N''-2-pyridinylguanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

: 504-29-0
2-aminopyridine

: 71079-18-0
N¹-cyclohexyl-N²-(2-methyl-4-quinolyl)carbodiimide

: 71080-09-6
N-Cyclohexyl-N'-(2-methyl-quinolin-4-yl)-N''-pyridin-2-yl-guanidine

Guidance literature:: In toluene; for 1h; Heating;
DOI:10.1021/jm00175a004

Reference yield:

: 71070-70-7
N-cyclohexyl-N'-4-(2-methylquinolyl)urea

: 71080-09-6
N-Cyclohexyl-N'-(2-methyl-quinolin-4-yl)-N''-pyridin-2-yl-guanidine

Guidance literature:: Multi-step reaction with 2 steps

1: Ph₃P, Et₃N / CCl₄; CH₂Cl₂ / 2 h / Heating

2: 23 percent / toluene / 1 h / Heating

With triethylamine; triphenylphosphine; In tetrachloromethane; dichloromethane; toluene;
DOI:10.1021/jm00175a004