Vincanol

Base Information

Chemical Name:Vincanol
CAS No.:19877-89-5
Molecular Formula:C19H24N2O
Molecular Weight:296.412
Hs Code.:
European Community (EC) Number:243-388-9
UNII:6H6JXC52ME
DSSTox Substance ID:DTXSID601043203
Nikkaji Number:J13.550J
Wikidata:Q27264906
NCI Thesaurus Code:C75106
ChEMBL ID:CHEMBL2104946
Mol file:19877-89-5.mol

Synonyms:Vincanol;19877-89-5;Vincanol [INN];Vincanolum;Vincanolum [INN-Latin];RGH 4406;EINECS 243-388-9;UNII-6H6JXC52ME;6H6JXC52ME;(3-alpha,14-alpha,16-alpha)-14,15-Dihydroeburnamenin-14-ol;Eburnamenin-14-ol, 14,15-dihydro-, (3-alpha,14-alpha,16-alpha)-;(41S,12S,13aS)-13a-ethyl-2,3,41,5,6,12,13,13a-octahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridin-12-ol;SCHEMBL1710248;CHEMBL2104946;DTXSID601043203;LS-63720;Q27264906;(15S,17S,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraen-17-ol

Suppliers and Price of Vincanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 9 raw suppliers

Chemical Property of Vincanol

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:108-110 °C
Refractive Index:1.719
Boiling Point:484.4 °C at 760 mmHg
PKA:14.30±0.40(Predicted)
Flash Point:246.8 °C
PSA：28.40000
Density:1.35 g/cm³
LogP:3.56320
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:296.188863393
Heavy Atom Count:22
Complexity:455

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(C2)O
Isomeric SMILES:CC[C@@]12CCCN3[C@@H]1C4=C(CC3)C5=CC=CC=C5N4[C@H](C2)O

Technology Process of Vincanol

There total 46 articles about Vincanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.5%

: 4880-88-0
vinburnine

: 473-99-4,2934-73-8,4201-84-7,19877-89-5,19877-90-8,38852-72-1,55028-40-5,55925-32-1,100102-02-1,119565-24-1,148347-60-8,148347-61-9
eburnamine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 0.5h; Ambient temperature;
DOI:10.1016/S0040-4020(01)80569-X

Reference yield: 10.0%

: 4880-88-0
vinburnine

: 19877-90-8
(15S,17S,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.0^2,7.0^8,18.0^15,19]nonadeca-2,4,6,8⁽¹⁸⁾-tetraen-17-ol

: 19877-89-5
(-)-isoeburnamine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at -25 ℃; for 1h;

Reference yield:

: 85588-92-7
(-)-methyl 1,2,3,4,6,7,12,12bα-octahydroindolo<2,3-a>quinolizine(1β-yl) pyruvate oxime

: 19877-89-5
(-)-isoeburnamine

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / NaOH / H₂O; ethane-1,2-diol / 3 h / 155 - 160 °C

2: 10 percent / LiAlH₄ / tetrahydrofuran / 1 h / -25 °C

With sodium hydroxide; lithium aluminium tetrahydride; In tetrahydrofuran; water; ethylene glycol;