Dctpalphas

Base Information

Chemical Name:Dctpalphas
CAS No.:64145-29-5
Molecular Formula:C₉H₁₆N₃O₁₂P₃S
Molecular Weight:483.226
Hs Code.:
Nikkaji Number:J788.136C

Synonyms:alpha-phosphorothioate-modified dCTP;dCTPalphaS;DCTTP;deoxycytidine thiotriphosphate;deoxycytidine thiotriphosphate, (R)-isomer;deoxycytidine thiotriphosphate, (S)-isomer

Suppliers and Price of Dctpalphas

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Biosynth Carbosynth
2'-Deoxycytidine-5'-O-(1-thiotriphosphate) sodium salt - 10 mM aqueous solution
2 mg
$ 625.00

Biosynth Carbosynth
2'-Deoxycytidine-5'-O-(1-thiotriphosphate) sodium salt - 10 mM aqueous solution
1 mg
$ 375.00

Biosynth Carbosynth
2'-Deoxycytidine-5'-O-(1-thiotriphosphate) sodium salt - 10 mM aqueous solution
5 mg
$ 1250.00

AK Scientific
Dctpalphas
5mg
$ 1737.00

AK Scientific
Dctpalphas
2mg
$ 893.00

Total 5 raw suppliers

Chemical Property of Dctpalphas

Chemical Property:

PSA：294.64000
LogP:0.16540
XLogP3:-3.9
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:13
Rotatable Bond Count:8
Exact Mass:482.96675512
Heavy Atom Count:28
Complexity:828

Purity/Quality:

97% ^*data from raw suppliers

2'-Deoxycytidine-5'-O-(1-thiotriphosphate) sodium salt - 10 mM aqueous solution ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(OC1N2C=CC(=NC2=O)N)COP(=S)(O)OP(=O)(O)OP(=O)(O)O)O
Isomeric SMILES:C1[C@@H]([C@H](O[C@H]1N2C=CC(=NC2=O)N)COP(=S)(O)OP(=O)(O)OP(=O)(O)O)O

Technology Process of Dctpalphas

There total 4 articles about Dctpalphas which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₈H₁₈N₃O₁₄P₃S^(4-)

: 64145-29-5
dCTP(α-S)

Guidance literature:: With ammonia; In acetonitrile; at 55 ℃; for 6h;
DOI:10.1021/ol050617r

Reference yield:

: 17182-39-7
(2R,3S,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl acetate

: 64145-29-5
dCTP(α-S)

Guidance literature:: Multi-step reaction with 3 steps

1: 79 percent / pyridine; sulfur / 16 h

2: 78 percent Spectr_. / DBU; tris(tetra-n-butylammonium) pyrophosphate / acetonitrile / 2 h

3: ammonia / acetonitrile / 6 h / 55 °C

With pyridine; ammonia; tris(tetra-n-butylammonium) hydrogen pyrophosphate; sulfur; 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile;
DOI:10.1021/ol050617r

Reference yield:

: 193093-37-7
Acetic acid (2R,3S,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-(2-thioxo-2λ⁵-[1,3,2]oxathiaphospholan-2-yloxymethyl)-tetrahydro-furan-3-yl ester

: 64145-29-5
dCTP(α-S)

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent Spectr_. / DBU; tris(tetra-n-butylammonium) pyrophosphate / acetonitrile / 2 h

2: ammonia / acetonitrile / 6 h / 55 °C

With ammonia; tris(tetra-n-butylammonium) hydrogen pyrophosphate; 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile;
DOI:10.1021/ol050617r