Norzoanthamine

Base Information

• Chemical Name: Norzoanthamine
• CAS No.: 164991-65-5
• Molecular Formula: C₂₉H₃₉NO₅
• Molecular Weight: 481.632
• Wikipedia: Norzoanthamine
• Wikidata: Q4391634
• Metabolomics Workbench ID: 175970
• ChEMBL ID: CHEMBL3139348
• Mol file: 164991-65-5.mol

Synonyms:norzoanthamine;norzoanthamine hydrochloride

Chemical Property of Norzoanthamine

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 645.413°C at 760 mmHg
• Flash Point: 344.134°C
• PSA: 72.91000
• Density: 1.272g/cm³
• LogP: 4.35140
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 0
• Exact Mass: 481.28282334
• Heavy Atom Count: 35
• Complexity: 1100

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CC2CN3C(C1)(O2)CCC4(C35CC6(C7CC(=CC(=O)C7CC(=O)C6C4(CC(=O)O5)C)C)C)C
• Isomeric SMILES: C[C@H]1C[C@@H]2CN3[C@](C1)(O2)CC[C@@]4([C@]35C[C@]6([C@@H]7CC(=CC(=O)[C@H]7CC(=O)[C@@H]6[C@@]4(CC(=O)O5)C)C)C)C

Technology Process of Norzoanthamine

There total 11 articles about Norzoanthamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

C34H49NO8 (1144161-46-5) → norzoanthamine (164991-65-5)

Guidance literature:

With water; acetic acid; at 100 ℃; for 21h;

DOI:10.1002/anie.200804546

Reference yield:

C2HF3O2*C29H39NO5 → norzoanthamine (164991-65-5)

Guidance literature:

With aluminum oxide; In methanol; at 20 ℃; for 1h;

Reference yield:

C35H57NO5Si2 → C29H37NO5 + norzoanthamine (164991-65-5)

Guidance literature:

With palladium diacetate; calcium carbonate; In acetonitrile; at 20 - 55 ℃; Inert atmosphere;

DOI:10.1002/anie.200904537

upstream raw materials:

C₃₀H₄₁NO₅

C₃₄H₄₉NO₈

C₃₄H₅₁NO₈

15,16-dihydronorzoanthamine

Refernces

• 1、 Kuramoto, Makoto,Hayashi, Koji,Yamaguchi, Kohji,Yada, Mika,Tsuji, Tomoko,Uemura, Daisuke. "Structure-activity relationship of norzoanthamine exhibiting significant inhibition of osteoporosis". . p. 771 - 779. Retrieved 1998.
• 2、 Yamashita, Daisuke,Murata, Yoshihisa,Hikage, Naotsuka,Takao, Ken-Ichi,Nakazaki, Atsuo,Kobayashi, Susumu. "Total synthesis of (-)-norzoanthamine". supporting information; experimental part. p. 1404 - 1406. Retrieved 2009/07/18.