1-Isonicotinoyl-4-(2-tolyl)thiosemicarbazide

Base Information

Chemical Name:1-Isonicotinoyl-4-(2-tolyl)thiosemicarbazide
CAS No.:74270-70-5
Molecular Formula:C14H14 N4 O S
Molecular Weight:286.357
Hs Code.:
DSSTox Substance ID:DTXSID10225282
ChEMBL ID:CHEMBL1399439
Mol file:74270-70-5.mol

Synonyms:1-isonicotinoyl-4-(2-tolyl)thiosemicarbazide;1-isonicotinoyl-4-(ortho-tolyl)thiosemicarbazide;1-ITTSC

Suppliers and Price of 1-Isonicotinoyl-4-(2-tolyl)thiosemicarbazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-Isonicotinoyl-4-(2-tolyl)thiosemicarbazide

Chemical Property:

PSA：108.67000
Density:1.32g/cm³
LogP:3.20760
XLogP3:2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:286.08883226
Heavy Atom Count:20
Complexity:344

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1NC(=S)NNC(=O)C2=CC=NC=C2

Technology Process of 1-Isonicotinoyl-4-(2-tolyl)thiosemicarbazide

There total 3 articles about 1-Isonicotinoyl-4-(2-tolyl)thiosemicarbazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 54-85-3,7640-37-1
isoniazid

: 614-69-7
2-tolyl isothiocyanate

: 74270-70-5
4-(2-methylphenyl)-1-(4-pyridoyl) thiosemicarbazide

Guidance literature:: With ethanol; for 0.0333333h; microwave irradiation;

Reference yield:

: 75-15-0,12122-00-8
carbon disulfide

: 54-85-3,7640-37-1
isoniazid

: 95-53-4
o-toluidine

: 74270-70-5
4-(2-methylphenyl)-1-(4-pyridoyl) thiosemicarbazide

Guidance literature:: carbon disulfide; o-toluidine; With potassium hydroxide; In ethanol; at 0 - 5 ℃; for 1h;

isoniazid; In ethanol; at 80 ℃; for 1h;
DOI:10.1007/s00044-014-1216-5