alpha-Zearalenol

Base Information

Chemical Name:alpha-Zearalenol
CAS No.:36455-72-8
Molecular Formula:C18H24 O5
Molecular Weight:320.386
Hs Code.:29322090
European Community (EC) Number:828-728-1
UNII:59D4EVJ5KC
DSSTox Substance ID:DTXSID8022402
Nikkaji Number:J3.201.624C
Wikipedia:Alpha-Zearalenol
Wikidata:Q27890390
Metabolomics Workbench ID:49563
ChEMBL ID:CHEMBL371463
Mol file:36455-72-8.mol

Synonyms:(-)-beta-zearalenol;(3R,7R,11E)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-1-one;1H-2-benzoxacyclotetradecin-1-one, 3,4,5,6,7,8,9,10-octahydro-7,14,16-trihydroxy-3-methyl-, (3S,7R,11E)-;3,4,5,6,7,8,9,10-octahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one;alpha-zearalenol;alpha-zearalenol, (cis)-isomer;beta-trans-zearalenol;beta-zearalenol;zearalenol

Suppliers and Price of alpha-Zearalenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
a-Zearalenol
1mg
$ 502.00

TRC
α-Zearalenol
10mg
$ 490.00

Sigma-Aldrich
α-Zearalenol
5mg
$ 321.00

Sigma-Aldrich
α-Zearalenol solution 10 μg/mL in acetonitrile, analytical standard
1ml
$ 631.00

Sigma-Aldrich
α-Zearalenol
10mg
$ 592.00

Cayman Chemical
α-Zearalenol ≥98%
1mg
$ 55.00

Cayman Chemical
α-Zearalenol ≥98%
10mg
$ 440.00

Cayman Chemical
α-Zearalenol ≥98%
5mg
$ 234.00

Apolloscientific
alphaZearalenolfromGiberellazeae
1mg
$ 143.00

Apolloscientific
alphaZearalenolfromGiberellazeae
10mg
$ 907.00

Total 16 raw suppliers

Chemical Property of alpha-Zearalenol

Chemical Property:

Vapor Pressure:3.4E-15mmHg at 25°C
Melting Point:158-161°C
Boiling Point:599°Cat760mmHg
PKA:7.61±0.60(Predicted)
Flash Point:217.9°C
PSA：86.99000
Density:1.174g/cm³
LogP:3.37140
Storage Temp.:2-8°C
Solubility.:≤20mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
XLogP3:4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:320.16237386
Heavy Atom Count:23
Complexity:408

Purity/Quality:

98%,99%, ^*data from raw suppliers

a-Zearalenol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn,T,F
Statements: 20/21/22-40-52/53-68/20/21/22-36-11-62-48/20-63-46-45
Safety Statements: 36/37-61-16-45-53

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC1CCCC(CCCC=CC2=C(C(=CC(=C2)O)O)C(=O)O1)O
Isomeric SMILES:C[C@H]1CCC[C@@H](CCC/C=C/C2=C(C(=CC(=C2)O)O)C(=O)O1)O
Description α-Zearalenol is a major hepatic metabolite of zearalenone , a mycotoxin produced by fungi in food and animal feeds. It is a less potent agonist of estrogen receptors than the parent compound. However, α-zearalenol has pronounced effects on uterotropic activity, sperm motility, and preimplantation embryonic development.
Uses α-Zearalenol is a mycotoxin produced by several species of Fusarium. α-Zearalenol exhibits pronounced estrogenic activity, being 3-fold more active than zearalenone. Contamination of grains, notably maize, by Fusarium species gives rise to high levels of zearalenol and is regarded as an important food quality issue for both humans and animal health. α- Zearalenol may be used as an analytical reference standard for the determination of the analyte in traditional medicinal herbs, human and animal urine by various chromatography techniques. The major metabolites of Zearalenone

Technology Process of alpha-Zearalenol

There total 15 articles about alpha-Zearalenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 445380-29-0
2,4-bis[(2-methoxyethoxy)methyl]-α-zearalenol

: 36455-72-8,40790-12-3
α-zearalenol

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; at 40 ℃;
DOI:10.1039/b005942k

Reference yield: 58.0%

: 17924-92-4,7645-23-0
zearalenone

: 71030-11-0,40790-12-3
beta-zearalenol

: 36455-72-8,40790-12-3
α-zearalenol

Guidance literature:: With sodium tetrahydroborate; In methanol; at 0 - 20 ℃; for 3h; Inert atmosphere;
DOI:10.1016/j.bmcl.2016.06.007

Reference yield: 40.0%

: 17924-92-4,7645-23-0
zearalenone

: 36455-72-8,40790-12-3
α-zearalenol

Guidance literature:: With dipotassium hydrogenphosphate; sodium chloride; In N,N-dimethyl-formamide; glucose, yeast extract, neopeptone, Streptomyces griseus ATCC 13273;
DOI:10.1021/jo00238a008