6,8-Bis(4-(dimethylamino)benzyl)-1,4-dihydroxy-7H-benzo(a)cyclohepten-7-one

Base Information

Chemical Name:6,8-Bis(4-(dimethylamino)benzyl)-1,4-dihydroxy-7H-benzo(a)cyclohepten-7-one
CAS No.:156306-84-2
Molecular Formula:C29H30 N2 O3
Molecular Weight:454.5601
Hs Code.:
NSC Number:676441
UNII:N8DHY7XG29
DSSTox Substance ID:DTXSID60166075
ChEMBL ID:CHEMBL1728065

Synonyms:MLS002702283;156306-84-2;N8DHY7XG29;NSC676441;UNII-N8DHY7XG29;NSC 676441;SMR001565845;6,8-Bis(4-(dimethylamino)benzyl)-1,4-dihydroxy-7H-benzo(a)cyclohepten-7-one;NSC-676441;6,8-Bis(4-(dimethylamino)benzyl)-1,4-dihydroxy-7H-benzo[a]cyclohepten-7-one;CHEMBL1728065;BDBM80081;cid_5466111;DTXSID60166075;6,4-dihydroxy-benzocyclohepten-7-one;NCI60_027048;SR-01000880013;SR-01000880013-2;6,8-Bis(p-dimethylaminobenzyl)-1, 4-dihydroxy-benzocyclohepten-7-one;6,8-bis[4-(dimethylamino)benzyl]-1,4-dihydroxy-benzocyclohepten-7-one;6,8-bis[(4-dimethylaminophenyl)methyl]-1,4-dihydroxy-benzo[7]annulen-7-one;6,8-bis[[4-(dimethylamino)phenyl]methyl]-1,4-bis(oxidanyl)benzo[7]annulen-7-one;6,8-bis[[4-(dimethylamino)phenyl]methyl]-1,4-dihydroxy-7-benzo[7]annulenone;6,8-bis[[4-(dimethylamino)phenyl]methyl]-1,4-dihydroxybenzo[7]annulen-7-one;7H-BENZOCYCLOHEPTEN-7-ONE, 6,8-BIS((4-(DIMETHYLAMINO)PHENYL)METHYL)-1,4-DIHYDROXY-

Suppliers and Price of 6,8-Bis(4-(dimethylamino)benzyl)-1,4-dihydroxy-7H-benzo(a)cyclohepten-7-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6,8-Bis(4-(dimethylamino)benzyl)-1,4-dihydroxy-7H-benzo(a)cyclohepten-7-one

Chemical Property:

Vapor Pressure:1.04E-20mmHg at 25°C
Boiling Point:708°Cat760mmHg
Flash Point:382°C
Density:1.253g/cm³
XLogP3:5.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:454.22564282
Heavy Atom Count:34
Complexity:695

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C1=CC=C(C=C1)CC2=CC3=C(C=CC(=C3C=C(C2=O)CC4=CC=C(C=C4)N(C)C)O)O

Technology Process of 6,8-Bis(4-(dimethylamino)benzyl)-1,4-dihydroxy-7H-benzo(a)cyclohepten-7-one

There total 3 articles about 6,8-Bis(4-(dimethylamino)benzyl)-1,4-dihydroxy-7H-benzo(a)cyclohepten-7-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 156306-82-0
1,4-dimethoxy-6,8-bis(p-dimethylaminobenzyl)benzocyclohepten-7-one

: 156306-84-2
6,8-Bis-(4-dimethylamino-benzyl)-1,4-dihydroxy-benzocyclohepten-7-one

Guidance literature:: With hydrogen bromide; In acetic acid; at 125 ℃;

Reference yield:

: 72101-55-4
1,4-dimethoxy-6,7,8,9-tetrahydro-5H-benzocycloheptene-7-one

: 156306-84-2
6,8-Bis-(4-dimethylamino-benzyl)-1,4-dihydroxy-benzocyclohepten-7-one

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / t-BuOK / 2-methyl-propan-2-ol / 0.75 h / Heating

2: 71 percent / 47percent aq. HBr / acetic acid / 125 °C

With potassium tert-butylate; hydrogen bromide; In acetic acid; tert-butyl alcohol;

Reference yield:

: 100-10-7
4-dimethylamino-benzaldehyde

: 156306-84-2
6,8-Bis-(4-dimethylamino-benzyl)-1,4-dihydroxy-benzocyclohepten-7-one

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / t-BuOK / 2-methyl-propan-2-ol / 0.75 h / Heating

2: 71 percent / 47percent aq. HBr / acetic acid / 125 °C

With potassium tert-butylate; hydrogen bromide; In acetic acid; tert-butyl alcohol;