Tetrahydro-2,6-dioxo-2H-pyran-3-propionic acid

Base Information

Chemical Name:Tetrahydro-2,6-dioxo-2H-pyran-3-propionic acid
CAS No.:40550-18-3
Molecular Formula:C8H10O5
Molecular Weight:186.164
Hs Code.:
European Community (EC) Number:254-972-8
NSC Number:166524
DSSTox Substance ID:DTXSID001246857
Nikkaji Number:J332.447H
Mol file:40550-18-3.mol

Synonyms:40550-18-3;Tetrahydro-2,6-dioxo-2H-pyran-3-propionic acid;3-(2,6-dioxooxan-3-yl)propanoic acid;EINECS 254-972-8;3-(2,6-dioxotetrahydro-2H-pyran-3-yl)propanoic acid;NSC166524;SCHEMBL1697173;DTXSID001246857;NSC 166524;NSC-166524;Tetrahydro-2,6-dioxo-2H-pyran-3-propanoic acid;3-(2,6-dioxotetrahydro-2H-pyran-3-yl)propanoicacid

Suppliers and Price of Tetrahydro-2,6-dioxo-2H-pyran-3-propionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 9 raw suppliers

Chemical Property of Tetrahydro-2,6-dioxo-2H-pyran-3-propionic acid

Chemical Property:

Vapor Pressure:1.51E-08mmHg at 25°C
Boiling Point:428.6°Cat760mmHg
Flash Point:180°C
PSA：80.67000
Density:1.337g/cm³
LogP:0.33100
XLogP3:-0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:186.05282342
Heavy Atom Count:13
Complexity:245

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)OC(=O)C1CCC(=O)O

Technology Process of Tetrahydro-2,6-dioxo-2H-pyran-3-propionic acid

There total 9 articles about Tetrahydro-2,6-dioxo-2H-pyran-3-propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 6940-58-5
pentane-1,3,5-tricarboxylic acid

: 40550-18-3
3-(2,6-dioxotetrahydro-2H-pyran-3-yl)propanoic acid

Guidance literature:: With thionyl chloride; In 1,2-dichloro-ethane; for 5h; Heating;
DOI:10.1002/hlca.19980810106

Reference yield:

: 99358-58-4
2,4-dicyano-2-(2-cyano-ethyl)-butyric acid

: 40550-18-3
3-(2,6-dioxotetrahydro-2H-pyran-3-yl)propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: concentrated aqueous hydrochloric acid

2: durch Erhitzen unter vermindertem Druck

With hydrogenchloride;
DOI:10.1021/jo01364a016

Reference yield:

: 1112-50-1
2,4-dicyano-2-(2-cyano-ethyl)-butyric acid amide

: 40550-18-3
3-(2,6-dioxotetrahydro-2H-pyran-3-yl)propanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: concentrated HCl

2: aqueous KOH-solution

3: Beim Erhitzen unter vermindertem Druck

With hydrogenchloride; potassium hydroxide;
DOI:10.1021/jo01364a016