4,7-dimethylallopsoralen

Base Information

• Chemical Name: 4,7-dimethylallopsoralen
• CAS No.: 27038-42-2
• Molecular Formula: C₁₃H₁₀O₃
• Molecular Weight: 214.221
• Hs Code.: 2932999099
• Mol file: 27038-42-2.mol

Synonyms:4,7-dimethylallopsoralen

Chemical Property of 4,7-dimethylallopsoralen

Chemical Property:

• Vapor Pressure: 4.67E-06mmHg at 25°C
• Boiling Point: 382.6°Cat760mmHg
• Flash Point: 185.2°C
• PSA: 43.35000
• Density: 1.273g/cm³
• LogP: 3.15600

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,7-dimethylallopsoralen

There total 5 articles about 4,7-dimethylallopsoralen which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

5-acetoxy-6-allyl-4,7-dimethylcoumarin (79049-89-1) → 4,7-dimethylallopsoralen (27038-42-2) + 4,7-dimethyl-5-acetoxy-6-(2'-bromopropyl)coumarin

Guidance literature:

With hydrogen bromide; In acetic acid; for 1h; Heating;

Reference yield:

6-allyl-5-hydroxy-4,7-dimethylcoumarin (96836-20-3) → 4,7-dimethylallopsoralen (27038-42-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / acetic anhydride / 1 h / Heating

2: 48 percent / 40percent hydrobromic acid / acetic acid / 1 h / Heating

With hydrogen bromide; In acetic anhydride; acetic acid;

Reference yield:

(5-Hydroxy-4,7-dimethyl-2-oxo-2H-chromen-6-yl)-acetaldehyde → 4,7-dimethylallopsoralen (27038-42-2)

Guidance literature:

With phosphoric acid; at 100 ℃; for 0.333333h; Yield given;

upstream raw materials:

5-acetoxy-6-allyl-4,7-dimethylcoumarin

6-allyl-5-hydroxy-4,7-dimethylcoumarin

Refernces

• 1、 Dall'Acqua,Vedaldi,Caffieri,Rodighiero. "Photoreaction between 4,7-dimethylallopsoralen and DNA: Isolation of a fluorescent cycloadduct between the furocoumarin and thymine". . p. 606 - 613. Retrieved 2007/10/02.