3-AMINOMETHYL-PHENYLACETIC ACID

Base Information

• Chemical Name: 3-AMINOMETHYL-PHENYLACETIC ACID
• CAS No.: 113520-43-7
• Molecular Formula: C9H11NO2
• Molecular Weight: 165.18900
• Hs Code.: 2922499990
• Mol file: 113520-43-7.mol

Synonyms:AB3035;S01-0872;

Chemical Property of 3-AMINOMETHYL-PHENYLACETIC ACID

Chemical Property:

• Boiling Point: 334.7±22.0 °C(Predicted)
• PKA: 4.17±0.10(Predicted)
• PSA: 63.32000
• Density: 1.206±0.06 g/cm3(Predicted)
• LogP: 1.47270

Purity/Quality:

98%min ^*data from raw suppliers

2-(3-(Aminomethyl)phenyl)aceticAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-AMINOMETHYL-PHENYLACETIC ACID

There total 2 articles about 3-AMINOMETHYL-PHENYLACETIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3-phthalimidomethyl-phenyl)-acetic acid (109091-42-1) → 2-(3-(aminomethyl)phenyl)acetic acid (113520-43-7)

Guidance literature:

With ethanol; hydrazine;

DOI:10.1021/ja01549a050

Reference yield:

phenylacetic acid (103-82-2) → 2-(3-(aminomethyl)phenyl)acetic acid (113520-43-7)

Guidance literature:

Multi-step reaction with 2 steps

1: concentrated sulfuric acid

2: ethanol; N₂H₄

With ethanol; sulfuric acid; hydrazine;

DOI:10.1021/ja01549a050

Reference yield:

2-(3-(aminomethyl)phenyl)acetic acid (113520-43-7) + tert-butyl 3-(5-carbamoyl-2-fluoro-4-hydroxyphenylsulfonamido)benzylcarbamate → 2-(3-(((2-(N-(3-(((tert-butoxycarbonyl)amino)methyl)phenyl)sulfamoyl)-4-carbamoyl-5-hydroxyphenyl)amino)methyl)phenyl)acetic acid

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In butan-1-ol; at 120 ℃; for 1h; Microwave irradiation;

upstream raw materials:

(3-phthalimidomethyl-phenyl)-acetic acid

phenylacetic acid