Technology Process of 1-Propanone, 1-[3,4-dichloro-5-(2-propenyloxy)phenyl]-
There total 7 articles about 1-Propanone, 1-[3,4-dichloro-5-(2-propenyloxy)phenyl]- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
N,N-dimethyl-formamide;
Ambient temperature;
DOI:10.1248/cpb.35.3215
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 42 percent / HNO3 / acetic anhydride; acetic acid / 1 h / 4 - 8 °C
2: 97 percent / potassium carbonate / dimethylformamide / 0.67 h / Heating
3: H2 / Pd-C (10percent) / ethyl acetate
4: 1.) BCl3, AlCl3; 2.) HCl (20percent)
5: 1.) NOSO4H (45percent); 2.) H3PO2 / 1.) H2SO4, THF, -25 to 0 deg C, 1.5 h; 2.) 6-10 deg C, 2 h
6: 88 percent / HBr (30percent) / acetic acid / 48 h / Heating
7: 94 percent / potassium carbonate / dimethylformamide / Ambient temperature
With
hydrogenchloride; aluminium trichloride; nitrosylsulfuric acid; hydrogen bromide; hydrogen; nitric acid; hypophosphorous acid; boron trichloride; potassium carbonate;
palladium on activated charcoal;
In
acetic anhydride; acetic acid; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1248/cpb.35.3215
- Guidance literature:
-
Multi-step reaction with 5 steps
1: H2 / Pd-C (10percent) / ethyl acetate
2: 1.) BCl3, AlCl3; 2.) HCl (20percent)
3: 1.) NOSO4H (45percent); 2.) H3PO2 / 1.) H2SO4, THF, -25 to 0 deg C, 1.5 h; 2.) 6-10 deg C, 2 h
4: 88 percent / HBr (30percent) / acetic acid / 48 h / Heating
5: 94 percent / potassium carbonate / dimethylformamide / Ambient temperature
With
hydrogenchloride; aluminium trichloride; nitrosylsulfuric acid; hydrogen bromide; hydrogen; hypophosphorous acid; boron trichloride; potassium carbonate;
palladium on activated charcoal;
In
acetic acid; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1248/cpb.35.3215