Phalloidin, 7-(5-((1,4-dioxo-4-((4-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenyl)amino)butyl)amino)-4-hydroxy-L-leucine)-

Base Information

Chemical Name:Phalloidin, 7-(5-((1,4-dioxo-4-((4-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenyl)amino)butyl)amino)-4-hydroxy-L-leucine)-
CAS No.:87876-31-1
Molecular Formula:C₄₇H₅₇F₃N₁₂O₁₂S
Molecular Weight:1071.1
Hs Code.:

Synonyms:BRN 5231461;Phalloidin, 7-(5-((1,4-dioxo-4-((4-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenyl)amino)butyl)amino)-4-hydroxy-L-leucine)-;87876-31-1;C47H57F3N12O12S;C47-H57-F3-N12-O12-S;LS-102554

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Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Phalloidin, 7-(5-((1,4-dioxo-4-((4-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenyl)amino)butyl)amino)-4-hydroxy-L-leucine)-

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.64g/cm³
XLogP3:0.1
Hydrogen Bond Donor Count:12
Hydrogen Bond Acceptor Count:18
Rotatable Bond Count:10
Exact Mass:1070.38917096
Heavy Atom Count:75
Complexity:2240

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1C(=O)NC2CC3=C(NC4=CC=CC=C34)SCC(C(=O)N5CC(CC5C(=O)N1)O)NC(=O)C(NC(=O)C(NC(=O)C(NC2=O)CC(C)(CNC(=O)CCC(=O)NC6=CC=C(C=C6)C7(N=N7)C(F)(F)F)O)C)C(C)O

Technology Process of Phalloidin, 7-(5-((1,4-dioxo-4-((4-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenyl)amino)butyl)amino)-4-hydroxy-L-leucine)-

There total 6 articles about Phalloidin, 7-(5-((1,4-dioxo-4-((4-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenyl)amino)butyl)amino)-4-hydroxy-L-leucine)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 17466-45-4
Phalloidin

: 87876-31-1
N^δ-<4-<(1-Azi-2,2,2-trifluorethyl)benzoyl>-β-alanyl>-δ-aminophalloin

Guidance literature:: Multi-step reaction with 4 steps

1: 70 percent / pyridine / 5 h / Ambient temperature

2: 59 percent / 2.5N NH₃ / methanol / 6 h

3: 83 percent / Et₃N / dimethylformamide; tetrahydrofuran / 16 h / Ambient temperature

4: 1) trifluoroacetic acid, 2) Et₃N / 1) CH₂Cl₂, RT, 10 min, 2) CH₃OH, 12 h

With ammonium hydroxide; triethylamine; trifluoroacetic acid; In tetrahydrofuran; pyridine; methanol; N,N-dimethyl-formamide;
DOI:10.1002/jlac.198319830909

Reference yield:

: 35167-99-8
O^δ7-Tosylphalloidin

: 87876-31-1
N^δ-<4-<(1-Azi-2,2,2-trifluorethyl)benzoyl>-β-alanyl>-δ-aminophalloin

Guidance literature:: Multi-step reaction with 3 steps

1: 59 percent / 2.5N NH₃ / methanol / 6 h

2: 83 percent / Et₃N / dimethylformamide; tetrahydrofuran / 16 h / Ambient temperature

3: 1) trifluoroacetic acid, 2) Et₃N / 1) CH₂Cl₂, RT, 10 min, 2) CH₃OH, 12 h

With ammonium hydroxide; triethylamine; trifluoroacetic acid; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1002/jlac.198319830909

Reference yield:

: 87736-89-8
1-<<4-<3-(trifluoromethyl)-3H-diazirin-3-yl>benzoyl>oxy>-2,5-pyrrolidinedione

: 87876-31-1
N^δ-<4-<(1-Azi-2,2,2-trifluorethyl)benzoyl>-β-alanyl>-δ-aminophalloin

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / 1N NaOH / methanol / 8 h / Ambient temperature

2: 1) Et₃N, chloroformic acid-isobutylester / 1) THF, -15 deg C, 8 min, 2) DMF, RT, 2 h

With sodium hydroxide; triethylamine; isobutyl chloroformate; In methanol;
DOI:10.1002/jlac.198319830909