1-Pyrrolidineacetic acid, 4-(4-chlorophenyl)-2-oxo-

Base Information

• Chemical Name: 1-Pyrrolidineacetic acid, 4-(4-chlorophenyl)-2-oxo-
• CAS No.: 113932-99-3
• Molecular Formula: C12H12ClNO3
• Molecular Weight: 253.685

Synonyms:

Chemical Property of 1-Pyrrolidineacetic acid, 4-(4-chlorophenyl)-2-oxo-

Chemical Property:

Purity/Quality:

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Technology Process of 1-Pyrrolidineacetic acid, 4-(4-chlorophenyl)-2-oxo-

There total 1 articles about 1-Pyrrolidineacetic acid, 4-(4-chlorophenyl)-2-oxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-[4-(p-chlorophenyl)-2-oxopyrrolidin-1-yl]-acetic acid ethyl ester (113933-11-2) → 2-[4-(p-chlorophenyl)-2-oxopyrrolidin-1-yl]-acetic acid (113932-99-3)

Guidance literature:

With potassium hydroxide; In methanol; hexane; ethyl acetate;

Reference yield:

piperazin-2-one (ketopiperazine) + 2-[4-(p-chlorophenyl)-2-oxopyrrolidin-1-yl]-acetic acid (113932-99-3) → 1-[4-(p-chlorophenyl)-2-oxopyrrolidin-1-ylacetyl]-3-oxopiperazine (113957-09-8)

Guidance literature:

In dichloromethane;

Reference yield:

triphenyl phosphite (101-02-0) + 2-[4-(p-chlorophenyl)-2-oxopyrrolidin-1-yl]-acetic acid (113932-99-3) + 1-phenylmethylpiperazine (2759-28-6) + maleic acid (110-16-7,26099-09-2) → 1-[4-(p-chlorophenyl)-2-oxopyrrolidin-1-ylacetyl]-4-benzylpiperazine maleate

Guidance literature:

In N-methyl-acetamide; acetone;

upstream raw materials:

2-[4-(p-chlorophenyl)-2-oxopyrrolidin-1-yl]-acetic acid ethyl ester

Downstream raw materials:

1-[4-(p-chlorophenyl)-2-oxopyrrolidin-1-ylacetyl]-3-oxopiperazine

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