2-((4-(2-Chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-2-pyridyl)methoxy)acetic acid

Base Information

Chemical Name:2-((4-(2-Chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-2-pyridyl)methoxy)acetic acid
CAS No.:113994-45-9
Molecular Formula:C20H20ClNO7
Molecular Weight:421.82800
Hs Code.:
UNII:7DYI36G762
DSSTox Substance ID:DTXSID50150625
Wikidata:Q27268126
Mol file:113994-45-9.mol

Synonyms:113994-45-9;2-((4-(2-Chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-2-pyridyl)methoxy)acetic acid;O-Des[2-aminoethyl]-O-carboxymethyl-dehydroamlodipine;UNII-7DYI36G762;7DYI36G762;O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine;3,5-Pyridinedicarboxylic acid, 2-((carboxymethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-, 3-ethyl 5-methyl ester;2-[[4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methylpyridin-2-yl]methoxy]acetic acid;SCHEMBL18157028;DTXSID50150625;AKOS040754723;PD150573;J-003046;Q27268126;Amlodipine metabolite M12 (O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine);2-((4-(2-Chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methylpyridin-2-yl)methoxy)acetic acid;2-[(carboxymethoxy)methyl]-4-(2-chlorophenyl)-6-methyl- 3-ethyl 5-methyl Ester 3,5-pyridinedicarboxylic Acid

Suppliers and Price of 2-((4-(2-Chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-2-pyridyl)methoxy)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
O-Des[2-aminoethyl]-O-carboxymethyldehydroamlodipine
2.5mg
$ 215.00

Total 7 raw suppliers

Chemical Property of 2-((4-(2-Chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-2-pyridyl)methoxy)acetic acid

Chemical Property:

Melting Point:75.5-80 °C
Boiling Point:571.8±50.0 °C(Predicted)
PKA:3.07±0.10(Predicted)
PSA：112.02000
Density:1.323±0.06 g/cm3(Predicted)
LogP:3.27490
Storage Temp.:-20°C Freezer
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:10
Exact Mass:421.0928297
Heavy Atom Count:29
Complexity:587

Purity/Quality:

>95% ^*data from raw suppliers

O-Des[2-aminoethyl]-O-carboxymethyldehydroamlodipine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(C(=C(N=C1COCC(=O)O)C)C(=O)OC)C2=CC=CC=C2Cl
Uses O-Des[2-aminoethyl]-O-carboxymethyl-dehydroamlodipine is the metablolite of Amlodipine (A633495), a long-acting calcium channel blocker that is commonly used as an anti-hypertensive in the treatment of cardiovascular conditions.

Technology Process of 2-((4-(2-Chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-2-pyridyl)methoxy)acetic acid

There total 2 articles about 2-((4-(2-Chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-2-pyridyl)methoxy)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 88150-42-9
2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine

: 113994-45-9
4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-2-(carboxymethoxy)methyl-6-methylpyridine

: 4-(2-chlorophenyl)-5-carboxy-2-(carboxymethoxy)methyl-3-ethoxycarbonyl-6-methylpyridine

: 113994-41-5
2-(2-Amino-ethoxymethyl)-4-(2-chloro-phenyl)-6-methyl-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester

Guidance literature:: With sodium hypochlorite; octabromotetrakis(2,6-dichlorophenyl)porphyrin Fe(III)Cl; water; In acetonitrile; at 80 ℃; for 0.166667h; Microwave irradiation;