N-{[(Benzyloxy)carbonyl]oxy}hex-3-enamide

Base Information

• Chemical Name: N-{[(Benzyloxy)carbonyl]oxy}hex-3-enamide
• CAS No.: 114142-22-2
• Molecular Formula: C14H17NO4
• Molecular Weight: 263.293
• DSSTox Substance ID: DTXSID70708804
• Mol file: 114142-22-2.mol

Synonyms:114142-22-2;N-{[(Benzyloxy)carbonyl]oxy}hex-3-enamide;DTXSID70708804

Chemical Property of N-{[(Benzyloxy)carbonyl]oxy}hex-3-enamide

Chemical Property:

• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 8
• Exact Mass: 263.11575802
• Heavy Atom Count: 19
• Complexity: 309

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC=CCC(=O)NOC(=O)OCC1=CC=CC=C1

Technology Process of N-{[(Benzyloxy)carbonyl]oxy}hex-3-enamide

There total 1 articles about N-{[(Benzyloxy)carbonyl]oxy}hex-3-enamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3E)-3-hexenoic hydroxamic acid (114142-24-4) + benzyl chloroformate (501-53-1,94274-21-2) → C14H17NO4 (114142-22-2)

Guidance literature:

Yield given;

DOI:10.1016/S0040-4039(01)91346-2

Reference yield: 53.0%

C14H17NO4 (114142-22-2) → Carbonic acid benzyl ester (S)-2-((R)-1-bromo-propyl)-4-oxo-azetidin-1-yl ester (114142-23-3,114779-97-4)

Guidance literature:

With water; bromine; potassium carbonate; In acetonitrile; at 0 - 20 ℃; for 0.0833333h;

DOI:10.1016/S0040-4039(01)91346-2

upstream raw materials:

(3E)-3-hexenoic hydroxamic acid

benzyl chloroformate

Downstream raw materials:

Carbonic acid benzyl ester (S)-2-((R)-1-bromo-propyl)-4-oxo-azetidin-1-yl ester