Benzoic acid, 4-[[4-(dimethylamino)phenyl]azo]-, (E)-

Base Information

• Chemical Name: Benzoic acid, 4-[[4-(dimethylamino)phenyl]azo]-, (E)-
• CAS No.: 114143-63-4
• Molecular Formula: C₁₅H₁₅N₃O₂
• Molecular Weight: 269.303
• Mol file: 114143-63-4.mol

Synonyms:4-{(E)-[4-(dimethylamino)phenyl]diazenyl}benzoic acid;.4-[4-(dimethylamino)phenylazo]benzoic acid;.4-[4'-(Dimethylamino)phenylazo]benzoic acid;.para-methyl red;.4-((4-(dimethylamino)phenyl)azo)benzoic acid;.4-[(4-Dimethylaminophenyl)azo]benzoic acid;

Chemical Property of Benzoic acid, 4-[[4-(dimethylamino)phenyl]azo]-, (E)-

Chemical Property:

• PSA: 65.26000
• LogP: 3.86620

Purity/Quality:

95%, 99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 4-[[4-(dimethylamino)phenyl]azo]-, (E)-

There total 9 articles about Benzoic acid, 4-[[4-(dimethylamino)phenyl]azo]-, (E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-amino-benzoic acid (150-13-0,159246-81-8,8014-65-1) + N,N-dimethyl-aniline (121-69-7,77733-26-7) → 4-[4-(dimethylamino)phenylazo]benzoic acid (114143-63-4,6268-49-1,114143-64-5)

Guidance literature:

4-amino-benzoic acid; With hydrogenchloride; sodium carbonate; sodium nitrite; at 0 ℃;

N,N-dimethyl-aniline; In water; at 0 - 20 ℃; Further stages.;

DOI:10.1039/b601120a

Reference yield: 91.8%

4-amino-benzoic acid (150-13-0,159246-81-8,8014-65-1) + 4-amino-N,N-dimethylaniline (99-98-9) → 4-[4-(dimethylamino)phenylazo]benzoic acid (114143-63-4,6268-49-1,114143-64-5)

Guidance literature:

4-amino-benzoic acid; With hydrogenchloride; sodium nitrite; In water; at 0 ℃; for 0.5h;

4-amino-N,N-dimethylaniline; With hydrogenchloride; In water; for 0.5h;

Reference yield: 53.0%

4-[4'-(Dimethylamino)phenylazo]benzoic acid methyl ester → 4-[4-(dimethylamino)phenylazo]benzoic acid (114143-63-4,6268-49-1,114143-64-5)

Guidance literature:

4-[4'-(Dimethylamino)phenylazo]benzoic acid methyl ester; With lithium hydroxide; In methanol; water; at 70 ℃; for 24h;

With hydrogenchloride; In methanol; water; pH=6;

DOI:10.1016/j.ejmech.2011.08.035

upstream raw materials:

cis-p-methyl red

4-amino-benzoic acid

N,N-dimethyl-aniline

4-methoxycarbonyl aniline

Downstream raw materials:

C₁₂₆H₂₄₅N₇O₂₈*C₁₅H₁₅N₃O₂

cis-p-methyl red

4-(4-Dimethylamino-phenylazo)-benzoic acid (2R,3S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-trityloxymethyl-tetrahydro-furan-3-yl ester