2-Amino-2-(hydroxymethyl)-4-methylpentanoic acid

Base Information

Chemical Name:2-Amino-2-(hydroxymethyl)-4-methylpentanoic acid
CAS No.:7522-44-3
Molecular Formula:C₇H₁₅NO₃
Molecular Weight:161.201
Hs Code.:2922509090
DSSTox Substance ID:DTXSID10370029
Mol file:7522-44-3.mol

Synonyms:7522-44-3;DL-2-ISOBUTYLSERINE;2-amino-2-(hydroxymethyl)-4-methylpentanoic acid;SCHEMBL3100826;DTXSID10370029

Suppliers and Price of 2-Amino-2-(hydroxymethyl)-4-methylpentanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
DL-2-ISOBUTYLSERINE 95.00%
5MG
$ 497.56

Total 8 raw suppliers

Chemical Property of 2-Amino-2-(hydroxymethyl)-4-methylpentanoic acid

Chemical Property:

Vapor Pressure:1.37E-05mmHg at 25°C
Melting Point:288-290 °C
Refractive Index:1.4500 (estimate)
Boiling Point:328.9ºC at 760 mmHg
PKA:2.13±0.41(Predicted)
Flash Point:152.7ºC
PSA：83.55000
Density:1.148g/cm3
LogP:0.50720
XLogP3:-2.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:161.10519334
Heavy Atom Count:11
Complexity:147

Purity/Quality:

98%Min ^*data from raw suppliers

DL-2-ISOBUTYLSERINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(CO)(C(=O)O)N

Technology Process of 2-Amino-2-(hydroxymethyl)-4-methylpentanoic acid

There total 2 articles about 2-Amino-2-(hydroxymethyl)-4-methylpentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51127-26-5
N-(5-Isobutyl-4-oxo-[1,3]dioxan-5-yl)-benzamide

: 7522-44-3,137503-93-6,137503-94-7
2-amino-2-(hydroxymethyl)-4-methylpentanoic acid

Guidance literature:: With hydrogenchloride;
DOI:10.1055/s-1973-22306

Reference yield:

: 7522-44-3,137503-93-6,137503-94-7
2-amino-2-(hydroxymethyl)-4-methylpentanoic acid

Guidance literature:: Serin, 1. CuSO4 (->Cu-Komplex), 2. Abtrennung von Cu;

Reference yield:

: 7522-44-3,137503-93-6,137503-94-7
2-amino-2-(hydroxymethyl)-4-methylpentanoic acid

: C₁₉H₂₉NO₅

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / methanol / 20 °C / Cooling with ice

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 96 h / 0 - 20 °C

With N-ethyl-N,N-diisopropylamine; sodium hydroxide; In methanol; dichloromethane;