(5-Amino-2-hydroxyphenyl)-1-piperidinylmethanone

Base Information

Chemical Name:(5-Amino-2-hydroxyphenyl)-1-piperidinylmethanone
CAS No.:114259-87-9
Molecular Formula:C12H16N2O2
Molecular Weight:220.271
Hs Code.:
DSSTox Substance ID:DTXSID501235677
Mol file:114259-87-9.mol

Synonyms:(5-Amino-2-hydroxyphenyl)-1-piperidinylmethanone;114259-87-9;SCHEMBL17774874;DTXSID501235677

Suppliers and Price of (5-Amino-2-hydroxyphenyl)-1-piperidinylmethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of (5-Amino-2-hydroxyphenyl)-1-piperidinylmethanone

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:220.121177757
Heavy Atom Count:16
Complexity:251

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCN(CC1)C(=O)C2=C(C=CC(=C2)N)O

Technology Process of (5-Amino-2-hydroxyphenyl)-1-piperidinylmethanone

There total 3 articles about (5-Amino-2-hydroxyphenyl)-1-piperidinylmethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 68507-73-3
(2-hydroxy-5-nitrophenyl)(piperidin-1-yl)methanone

: 114259-87-9
(5-Amino-2-hydroxy-phenyl)-piperidin-1-yl-methanone

Guidance literature:: With hydrogen; nickel; In ethanol; under 2206.5 Torr;

Reference yield:

: 110-89-4
piperidine

: 114259-87-9
(5-Amino-2-hydroxy-phenyl)-piperidin-1-yl-methanone

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) thionyl chloride, 2.) triethylamine / 1.) benzene, reflux, 2.) reflux

2: H₂ / Raney nickel / ethanol / 2206.5 Torr

With thionyl chloride; hydrogen; triethylamine; nickel; In ethanol;

Reference yield:

: 96-97-9
5-nitrosalicylic acid

: 114259-87-9
(5-Amino-2-hydroxy-phenyl)-piperidin-1-yl-methanone

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) thionyl chloride, 2.) triethylamine / 1.) benzene, reflux, 2.) reflux

2: H₂ / Raney nickel / ethanol / 2206.5 Torr

With thionyl chloride; hydrogen; triethylamine; nickel; In ethanol;