3(2H)-Pyridazinone, 6-chloro-5-methoxy-

Base Information

• Chemical Name: 3(2H)-Pyridazinone, 6-chloro-5-methoxy-
• CAS No.: 114333-03-8
• Molecular Formula: C5H5ClN2O2
• Molecular Weight: 160.56
• European Community (EC) Number: 866-857-5
• DSSTox Substance ID: DTXSID30356229
• Wikidata: Q82135472
• Mol file: 114333-03-8.mol

Synonyms:114333-03-8;6-chloro-5-methoxy-2,3-dihydropyridazin-3-one;3(2H)-Pyridazinone, 6-chloro-5-methoxy-;3-chloro-4-methoxy-1H-pyridazin-6-one;6-Chloro-5-methoxypyridazin-3(2H)-one;6-Chloro-5-methoxy-2H-pyridazin-3-one/3-chlor-6-hydroxy-4-methoxypyridazin;SCHEMBL22042633;DTXSID30356229;MFCD04971422;PS-18021;CS-0185220;FT-0745393;EN300-309232;F20647

Chemical Property of 3(2H)-Pyridazinone, 6-chloro-5-methoxy-

Chemical Property:

• PSA: 55.24000
• LogP: 0.84420
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 160.0039551
• Heavy Atom Count: 10
• Complexity: 222

Purity/Quality:

99%, ^*data from raw suppliers

6-Chloro-5-methoxy-2,3-dihydropyridazin-3-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=O)NN=C1Cl

Technology Process of 3(2H)-Pyridazinone, 6-chloro-5-methoxy-

There total 3 articles about 3(2H)-Pyridazinone, 6-chloro-5-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,6-dichloro-4-methoxy-1,2-dihydropyridazine (70952-62-4) → 3-Chlor-6-hydroxy-4-methoxypyridazin (114333-03-8)

Guidance literature:

With water; potassium acetate; acetic acid; at 140 ℃; for 1h; Microwave irradiation;

Reference yield:

→ 5-Methoxy-6-chlor-2H-pyridazinon-(3) (114333-03-8)

Guidance literature:

Neben anderen Verb. aus: 3.6-Dichlor-4-methoxy-pyridazin, Perphthalsaeure, Ae.;

DOI:10.1248/cpb.10.643

Reference yield:

→ 3-Chlor-6-hydroxy-4-methoxypyridazin (114333-03-8)

Guidance literature:

3-Chlor-4,6-dimethoxy-pyridazin, sd. wss. HCl; S.80;

DOI:10.1007/BF00908906

upstream raw materials:

3,6-dichloro-4-methoxy-1,2-dihydropyridazine