2,3,4,5-Tetrafluoro-6-hydroxy-N-phenylbenzamide

Base Information

Chemical Name:2,3,4,5-Tetrafluoro-6-hydroxy-N-phenylbenzamide
CAS No.:114546-82-6
Molecular Formula:C13H7F4NO2
Molecular Weight:285.198
Hs Code.:
DSSTox Substance ID:DTXSID60549662
Wikidata:Q82428777
Mol file:114546-82-6.mol

Synonyms:114546-82-6;2,3,4,5-Tetrafluoro-6-hydroxy-N-phenylbenzamide;tetra-fluorosalicylanilide;DTXSID60549662

Suppliers and Price of 2,3,4,5-Tetrafluoro-6-hydroxy-N-phenylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2,3,4,5-Tetrafluoro-6-hydroxy-N-phenylbenzamide

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:285.04129111
Heavy Atom Count:20
Complexity:351

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)NC(=O)C2=C(C(=C(C(=C2F)F)F)F)O

Technology Process of 2,3,4,5-Tetrafluoro-6-hydroxy-N-phenylbenzamide

There total 4 articles about 2,3,4,5-Tetrafluoro-6-hydroxy-N-phenylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 96386-10-6
α-pentafluorophenyl-N-phenylnitrone

: 114546-82-6
tetrafluorosalicylanilide

Guidance literature:: With hydrogenchloride; In N,N-dimethyl-formamide; at 100 - 110 ℃; for 1h;
DOI:10.1007/BF01557523

Reference yield:

: 114546-83-7
N-phenyl-N-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine

: 106000-41-3
10,11-dihydro-1,2,3,4-tetrafluorodibenz<1,4>oxazepine

: 114546-82-6
tetrafluorosalicylanilide

Guidance literature:: With potassium fluoride; In N,N-dimethyl-formamide; at 100 - 110 ℃; for 5h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1007/BF01557523

Reference yield:

: 114546-83-7
N-phenyl-N-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine

: 114546-82-6
tetrafluorosalicylanilide

Guidance literature:: Multi-step reaction with 2 steps

1: KF / dimethylformamide / 9 h / 60 °C

2: dimethylformamide / 1 h / 100 - 110 °C

With potassium fluoride; In N,N-dimethyl-formamide;
DOI:10.1007/BF01557523