11-Ketoprogesterone

Base Information

Chemical Name:11-Ketoprogesterone
CAS No.:516-15-4
Molecular Formula:C21H28O3
Molecular Weight:328.452
Hs Code.:
European Community (EC) Number:208-222-1
UNII:9Y1Y86O4T5
DSSTox Substance ID:DTXSID101031475
Nikkaji Number:J6.304E
Wikipedia:11-Ketoprogesterone
Wikidata:Q27273369
Pharos Ligand ID:UTVFWHSXZMM7
Metabolomics Workbench ID:87118
ChEMBL ID:CHEMBL284253
Mol file:516-15-4.mol

Synonyms:11-keto-P;11-keto-progesterone;11-ketoprogesterone;11-oxoprogesterone;4-pregnene-3,11,20-trione;Bio-66

Suppliers and Price of 11-Ketoprogesterone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
11-Ketoprogesterone
500mg
$ 135.00

TCI Chemical
4-Pregnene-3,11,20-trione >97.0%(HPLC)
1g
$ 129.00

Sigma-Aldrich
11-KETOPROGESTERONE Aldrich
250mg
$ 144.00

Medical Isotopes, Inc.
11-Ketoprogesterone
500 mg
$ 290.00

Chem-Impex
4-Pregnene-3,11,20-trione,97%(HPLC) 97%(HPLC)
1G
$ 127.68

American Custom Chemicals Corporation
4-PREGNENE-3,11,20-TRIONE 95.00%
1G
$ 650.16

AK Scientific
11-Ketoprogesterone
1g
$ 226.00

Total 52 raw suppliers

Chemical Property of 11-Ketoprogesterone

Chemical Property:

Appearance/Colour:white crystalline
Vapor Pressure:1.17E-09mmHg at 25°C
Melting Point:170-175 °C (lit.)
Refractive Index:1.55
Boiling Point:487.6 °C at 760 mmHg
Flash Point:209.3 °C
PSA：51.21000
Density:1.14 g/cm³
LogP:3.90250
Storage Temp.:Refrigerator
Solubility.:Chloroform (Sparingly), Ethyl Acetate (Slightly)
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:328.20384475
Heavy Atom Count:24
Complexity:660

Purity/Quality:

99%, ^*data from raw suppliers

11-Ketoprogesterone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC(=O)C1CCC2C1(CC(=O)C3C2CCC4=CC(=O)CCC34C)C
Isomeric SMILES:CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC(=O)[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C
General Description 11-Ketoprogesterone (also known as 11-Oxoprogesterone, Ketogestin, or DG 322A) is a steroid hormone derivative of progesterone, characterized by the presence of a ketone group at the 11-position of the steroid backbone. It shares structural similarities with progesterone but exhibits distinct biological activity, potentially influencing endocrine pathways. While its exact physiological role remains less defined compared to progesterone, it may interact with steroid hormone receptors or serve as an intermediate in steroid metabolism. Further research is needed to fully elucidate its functional significance.

Technology Process of 11-Ketoprogesterone

There total 32 articles about 11-Ketoprogesterone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%