ORG 9943

Base Information

• Chemical Name: ORG 9943
• CAS No.: 119302-86-2
• Molecular Formula: C30H51 N2 O3 . Br
• Molecular Weight: 567.651
• Mol file: 119302-86-2.mol

Synonyms:Pyrrolidinium,1-[(2b,3a,5a,16b,17b)-3,17-dihydroxy-2-(4-morpholinyl)androstan-16-yl]-1-(2-propenyl)-,bromide (9CI); 17-Desacetylrocuronium; Org 9943

Chemical Property of ORG 9943

Chemical Property:

• Melting Point: >196°C (dec.)
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 52.93000
• Density: g/cm³
• LogP: 0.73740
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

98%,99%, ^*data from raw suppliers

17-DesacetylRocuroniumBromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A metabolite 17-Desacetyl Rocuronium Bromide (Rocuronium EP Impurity C) is a metabolite of Rocuronium (R639500), in human plasma.

Technology Process of ORG 9943

There total 2 articles about ORG 9943 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

rocuronium bromide → (2β,3α,5α,16β,17β)-2-(4-morpholinyl)-16-(1-pyrrolidinyl)-3-hydroxy-17-acetoxyandrostane (119302-24-8) + (2β,3α,5α,16β,17β)-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol (119302-20-4) + 1-[(2β, 3α, 5α, 16β, 17β)-2-(4-morpholinyl)-androstan-16-yl-]-1-(2-propenyl)-pyrrolidinium bromide-3,17-diol (119302-86-2)

Guidance literature:

In dimethyl acetamide (DMA); for 3h; Product distribution / selectivity; Heating / reflux;

Reference yield:

rocuronium bromide → (2β,3α,5α,16β,17β)-2-(4-morpholinyl)-16-(1-pyrrolidinyl)-3-hydroxy-17-acetoxyandrostane (119302-24-8) + 1-[(2β, 3α, 5α, 16β, 17β)-2-(4-morpholinyl)-androstan-16-yl-]-1-(2-propenyl)-pyrrolidinium bromide-3,17-diol (119302-86-2)

Guidance literature:

In 2,4-dimethylpentan-3-one; for 16h; Product distribution / selectivity; Heating / reflux;

Refernces