1-[5-(N-Methoxyethanimidoyl)thiophen-2-yl]ethan-1-one

Base Information

Chemical Name:1-[5-(N-Methoxyethanimidoyl)thiophen-2-yl]ethan-1-one
CAS No.:114774-08-2
Molecular Formula:C9H11NO2S
Molecular Weight:197.258
Hs Code.:
DSSTox Substance ID:DTXSID10702866
Mol file:114774-08-2.mol

Synonyms:114774-08-2;DTXSID10702866;1-[5-(N-Methoxyethanimidoyl)thiophen-2-yl]ethan-1-one

Suppliers and Price of 1-[5-(N-Methoxyethanimidoyl)thiophen-2-yl]ethan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1-[5-(N-Methoxyethanimidoyl)thiophen-2-yl]ethan-1-one

Chemical Property:

PSA：66.90000
LogP:2.32110
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:197.05104977
Heavy Atom Count:13
Complexity:228

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=NOC)C1=CC=C(S1)C(=O)C

Technology Process of 1-[5-(N-Methoxyethanimidoyl)thiophen-2-yl]ethan-1-one

There total 3 articles about 1-[5-(N-Methoxyethanimidoyl)thiophen-2-yl]ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 108-24-7
acetic anhydride

: 114773-97-6
2-(α-methoxyimino)ethylthiophene

: 114774-08-2
5-acetyl-2-(α-methoxyimino)ethylthiophene

Guidance literature:: With PPA; at 100 ℃; for 9h;
DOI:10.1055/s-1992-26245

Reference yield:

: 88-15-3,97511-16-5
2-Acetylthiophene

: 114774-08-2
5-acetyl-2-(α-methoxyimino)ethylthiophene

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / Na₂CO₃, AcOH / methanol; H₂O / 2 h / Heating; pH 4.5

2: 64 percent / polyphosphoric acid / 9 h / 100 °C

With PPA; sodium carbonate; acetic acid; In methanol; water;
DOI:10.1055/s-1992-26245

Reference yield:

: 1956-45-2,92313-45-6,92313-54-7
2-acetylthiophene oxime

: 114774-08-2
5-acetyl-2-(α-methoxyimino)ethylthiophene

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / NaOH / dimethylformamide; H₂O / 0.5 h / 10 °C

2: 64 percent / polyphosphoric acid / 9 h / 100 °C

With sodium hydroxide; PPA; In water; N,N-dimethyl-formamide;
DOI:10.1055/s-1992-26245