7alpha,27-Dihydroxycholesterol

Base Information

Chemical Name:7alpha,27-Dihydroxycholesterol
CAS No.:4725-24-0
Molecular Formula:C₂₇H₄₆O₃
Molecular Weight:418.66
Hs Code.:
DSSTox Substance ID:DTXSID701311542
Nikkaji Number:J575.886F
Wikidata:Q28487682
Pharos Ligand ID:L5FNHZCJF8K7
Metabolomics Workbench ID:36756
ChEMBL ID:CHEMBL4788277
Mol file:4725-24-0.mol

Synonyms:cholest-5-ene-3,7,27-triol

Suppliers and Price of 7alpha,27-Dihydroxycholesterol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
7-ALPHA-27-DIHYDROXYCHOLESTEROL 95.00%
5MG
$ 495.34

Total 2 raw suppliers

Chemical Property of 7alpha,27-Dihydroxycholesterol

Chemical Property:

Vapor Pressure:1.63E-14mmHg at 25°C
Boiling Point:552.6°Cat760mmHg
PKA:14.11±0.70(Predicted)
Flash Point:232.6°C
PSA：60.69000
Density:1.08g/cm³
LogP:5.33190
XLogP3:6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:418.34469533
Heavy Atom Count:30
Complexity:644

Purity/Quality:

99% ^*data from raw suppliers

7-ALPHA-27-DIHYDROXYCHOLESTEROL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CCCC(C)C1CCC2C1(CCC3C2C(C=C4C3(CCC(C4)O)C)O)C)CO
Isomeric SMILES:C[C@H](CCCC(C)CO)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C=C4[C@@]3(CC[C@@H](C4)O)C)O)C
Uses 7α,27-Dihydroxycholesterol is used in the study of immunochemistry. It is a potent and selective agonist of EB12.7α,27-Dihydroxycholesterol is also studied in biochemical methods as one of several oxysterols found in human plasma using HPLC-MS and incorporating charg-tagging and high-resolution mass spectrometry.

Technology Process of 7alpha,27-Dihydroxycholesterol

There total 4 articles about 7alpha,27-Dihydroxycholesterol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: Acetic acid (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-acetoxy-1,5-dimethyl-hexyl)-7-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester

: 4725-24-0
5-cholesten-3β,7α,27-triol

: 240129-43-5
7β,27-dihydroxycholesterol

Guidance literature:: With methanol; potassium hydroxide; at 50 ℃; for 1h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1016/0039-128X(93)90048-R

Reference yield:

: 4725-24-0,144300-24-3,149055-91-4
5-Cholesten-3β.7α.26-triol

Guidance literature:: 5-Cholesten-3β.26-diol-acetat, 1.) Cu(I)Br, Eisessig, tert.Butylperbenzoat; 2.)Rk. mit LiAlH4;
DOI:10.1111/j.1432-1033.1973.tb02902.x