3-Benzoyl-4-(2-methylphenylamino)-8-methoxyquinoline

Base Information

Chemical Name:3-Benzoyl-4-(2-methylphenylamino)-8-methoxyquinoline
CAS No.:115607-64-2
Molecular Formula:C24H20N2O2
Molecular Weight:368.435
Hs Code.:
ChEMBL ID:CHEMBL115239
DSSTox Substance ID:DTXSID60433971
Nikkaji Number:J510.408D
Wikidata:Q82248259
Mol file:115607-64-2.mol

Synonyms:CHEMBL115239;115607-64-2;3-Benzoyl-4-(2-methylphenylamino)-8-methoxyquinoline;SCHEMBL10499646;DTXSID60433971;QGFLHWNLAOUSPQ-UHFFFAOYSA-N;[8-methoxy-4-(2-methylanilino)quinolin-3-yl]-phenylmethanone;BDBM50001233;(8-Methoxy-4-o-tolylamino-quinolin-3-yl)-phenyl-methanone

Suppliers and Price of 3-Benzoyl-4-(2-methylphenylamino)-8-methoxyquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 3-Benzoyl-4-(2-methylphenylamino)-8-methoxyquinoline

Chemical Property:

XLogP3:6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:368.152477885
Heavy Atom Count:28
Complexity:519

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1NC2=C3C=CC=C(C3=NC=C2C(=O)C4=CC=CC=C4)OC

Technology Process of 3-Benzoyl-4-(2-methylphenylamino)-8-methoxyquinoline

There total 4 articles about 3-Benzoyl-4-(2-methylphenylamino)-8-methoxyquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

: 115607-87-9
3-benzoyl-4-chloro-8-methoxyquinoline

: 95-53-4
o-toluidine

: 115607-64-2
3-benzoyl-4-(2-methylphenylamino)-8-methoxyquinoline

Guidance literature:: In 1,4-dioxane; for 1h; Heating;
DOI:10.1021/jm00096a018

Reference yield: 25.8%

methanolic ammonia: methanolic ammonia

: 115607-87-9
3-benzoyl-4-chloro-8-methoxyquinoline

: 95-53-4
o-toluidine

: 115607-64-2
3-benzoyl-4-(2-methylphenylamino)-8-methoxyquinoline

Guidance literature:: In 1,4-dioxane; dichloromethane;

Reference yield:

: 115607-86-8
3-benzoyl-8-methoxyquinolin-4(1H)-one

: 115607-64-2
3-benzoyl-4-(2-methylphenylamino)-8-methoxyquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: POCl₃ / CHCl₃ / 0.75 h / Heating

2: 26 percent / dioxane / 1 h / Heating

With trichlorophosphate; In 1,4-dioxane; chloroform;
DOI:10.1021/jm00096a018