(3aR)-3a,4,5,6,6aβ,7,9aβ,9bα-Octahydro-4β-acetoxy-6,9-dimethyl-6β-hydroxy-3-methyleneazuleno[4,5-b]furan-2(3H)-one

Base Information

• Chemical Name: (3aR)-3a,4,5,6,6aβ,7,9aβ,9bα-Octahydro-4β-acetoxy-6,9-dimethyl-6β-hydroxy-3-methyleneazuleno[4,5-b]furan-2(3H)-one
• CAS No.: 20482-33-1
• Molecular Formula: C₁₇H₂₂O₅
• Molecular Weight: 306.359
• Mol file: 20482-33-1.mol

Synonyms:Azuleno[4,5-b]furan-2(3H)-one,4-(acetyloxy)-3a,4,5,6,6a,7,9a,9b-octahydro-6-hydroxy-6,9-dimethyl-3-methylene-,[3aR-(3aa,4a,6a,6aa,9aa,9bb)]-; Guaia-3,11(13)-dien-12-oic acid, 6a,8,10-trihydroxy-, 12,6-lactone, 8-acetate (8CI);Cumambrin A; Cumambrin B acetate

Chemical Property of (3aR)-3a,4,5,6,6aβ,7,9aβ,9bα-Octahydro-4β-acetoxy-6,9-dimethyl-6β-hydroxy-3-methyleneazuleno[4,5-b]furan-2(3H)-one

Chemical Property:

• Vapor Pressure: 2.73E-10mmHg at 25°C
• Boiling Point: 457.4°Cat760mmHg
• Flash Point: 164.7°C
• PSA: 72.83000
• Density: 1.23g/cm³
• LogP: 1.75300

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (3aR)-3a,4,5,6,6aβ,7,9aβ,9bα-Octahydro-4β-acetoxy-6,9-dimethyl-6β-hydroxy-3-methyleneazuleno[4,5-b]furan-2(3H)-one

There total 3 articles about (3aR)-3a,4,5,6,6aβ,7,9aβ,9bα-Octahydro-4β-acetoxy-6,9-dimethyl-6β-hydroxy-3-methyleneazuleno[4,5-b]furan-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

angeloylcumambrin-B → cumambrin A (20482-33-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 10percent KOH / dioxane

2: pyridine

With pyridine; potassium hydroxide; In 1,4-dioxane;

DOI:10.1016/0031-9422(81)83100-7

Reference yield:

cumambrin B (21982-83-2) + acetic anhydride (108-24-7) → cumambrin A (20482-33-1)

Guidance literature:

With pyridine;

DOI:10.1016/0031-9422(81)83100-7

Reference yield:

→ cumambrin A (20482-33-1)

Guidance literature:

Aus 10 mit Eg.-anhydrid in Py.;

DOI:10.1021/jo00985a028

upstream raw materials:

cumambrin B

acetic anhydride