4,6-Dimethoxy-2-(phenylmethanesulfonyl)pyrimidine

Base Information

Chemical Name:4,6-Dimethoxy-2-(phenylmethanesulfonyl)pyrimidine
CAS No.:116022-39-0
Molecular Formula:C₁₃H₁₄N₂O₄S
Molecular Weight:294.331
Hs Code.:
DSSTox Substance ID:DTXSID40596659
Wikidata:Q82491963
Mol file:116022-39-0.mol

Synonyms:116022-39-0;4,6-Dimethoxy-2-(phenylmethanesulfonyl)pyrimidine;SCHEMBL7807155;DTXSID40596659

Suppliers and Price of 4,6-Dimethoxy-2-(phenylmethanesulfonyl)pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4,6-Dimethoxy-2-(phenylmethanesulfonyl)pyrimidine

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:294.06742811
Heavy Atom Count:20
Complexity:378

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC(=NC(=N1)S(=O)(=O)CC2=CC=CC=C2)OC

Technology Process of 4,6-Dimethoxy-2-(phenylmethanesulfonyl)pyrimidine

There total 1 articles about 4,6-Dimethoxy-2-(phenylmethanesulfonyl)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-benzylsulfanyl-4,6-dimethoxy-pyrimidine

: 116022-39-0
4,6-dimethoxy-2-phenylmethanesulfonyl-pyrimidine

Guidance literature:: With Oxone; In methanol; at 20 ℃;
DOI:10.1002/(SICI)1096-9063(199606)47:2<115::AID-PS397>3.0.CO;2-R

Reference yield:

: 116022-39-0
4,6-dimethoxy-2-phenylmethanesulfonyl-pyrimidine

: 110284-78-1
2-(4',6'-dimethoxypyrimidine-2'-yl)oxy-benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 29 percent / K₂CO₃ / butan-2-one

2: 86.5 percent / aq. NaOH / methanol / 1.5 h / 20 °C

With sodium hydroxide; potassium carbonate; In methanol; butanone; 1: Substitution / 2: Hydrolysis;
DOI:10.1002/(SICI)1096-9063(199606)47:2<115::AID-PS397>3.0.CO;2-R

Reference yield:

: 116022-39-0
4,6-dimethoxy-2-phenylmethanesulfonyl-pyrimidine

: Methyl O-(4,6-dimethoxy-5-chloropyrimidin-2-yl)salicylate

Guidance literature:: Multi-step reaction with 2 steps

1: 29 percent / K₂CO₃ / butan-2-one

2: 76.1 percent / N-chlorosuccinimide / CCl₄ / 5 h / Heating

With N-chloro-succinimide; potassium carbonate; In tetrachloromethane; butanone; 1: Substitution / 2: Chlorination;
DOI:10.1002/(SICI)1096-9063(199606)47:2<115::AID-PS397>3.0.CO;2-R