2-(2-Methylphenyl)-2,3-dihydro-4H-1-benzopyran-4-one

Base Information

• Chemical Name: 2-(2-Methylphenyl)-2,3-dihydro-4H-1-benzopyran-4-one
• CAS No.: 116115-46-9
• Molecular Formula: C16H14O2
• Molecular Weight: 238.286
• DSSTox Substance ID: DTXSID00555242
• Nikkaji Number: J2.971.086D
• Mol file: 116115-46-9.mol

Synonyms:116115-46-9;2-(o-Tolyl)chroman-4-one;2-(2-methylphenyl)-3,4-dihydro-2H-1-benzopyran-4-one;SCHEMBL8093292;2-(2-Methylphenyl)-2,3-dihydro-4H-1-benzopyran-4-one;DTXSID00555242

Chemical Property of 2-(2-Methylphenyl)-2,3-dihydro-4H-1-benzopyran-4-one

Chemical Property:

• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 238.099379685
• Heavy Atom Count: 18
• Complexity: 312

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=CC=C1C2CC(=O)C3=CC=CC=C3O2

Technology Process of 2-(2-Methylphenyl)-2,3-dihydro-4H-1-benzopyran-4-one

There total 2 articles about 2-(2-Methylphenyl)-2,3-dihydro-4H-1-benzopyran-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

2,3-dihydro-4H-1-benzopyran-4-one (491-37-2) + 2-methylphenyl bromide (95-46-5) → 2-o-tolylchroman-4-one (116115-46-9)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; potassium hydrogencarbonate; tri tert-butylphosphoniumtetrafluoroborate; In water; at 100 ℃; for 3h; chemoselective reaction; Inert atmosphere;

DOI:10.1002/adsc.201000810

Reference yield:

2'-Hydroxy-2-methyl-chalkon (42220-74-6) → 2-o-tolylchroman-4-one (116115-46-9)

Guidance literature:

With methanesulfonic acid; In acetic acid; for 2h; Reflux;

DOI:10.3184/174751917X14837116219573

Reference yield:

thiazoline-2,4-dione (2295-31-0) + 2-o-tolylchroman-4-one (116115-46-9) → 2-(o-tolyl)-1,2-dihydro (4H) thieno<2,3c>benzopyrane-4-one

Guidance literature:

With piperidine; In ethanol; at 78 ℃; for 20h;

DOI:10.3184/174751917X14837116219573

upstream raw materials:

2,3-dihydro-4H-1-benzopyran-4-one

2-methylphenyl bromide

2'-Hydroxy-2-methyl-chalkon

Downstream raw materials:

2-(2-methylphenyl)-4H-chromen-4-one

C₁₇H₁₇N₃O₂

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 116115-46-9 4H-1-Benzopyran-4-one, 2,3-dihydro-2-(2-methylphenyl)-

Send

Send

Metric Ton KG G Pound L ML

Send

Send