2-Methyl-3-(2,3,4-trimethoxyphenyl)oxirane

Base Information

Chemical Name:2-Methyl-3-(2,3,4-trimethoxyphenyl)oxirane
CAS No.:116145-29-0
Molecular Formula:C₁₂H₁₆O₄
Molecular Weight:224.257
Hs Code.:
DSSTox Substance ID:DTXSID201267027
Mol file:116145-29-0.mol

Synonyms:2-Methyl-3-(2,3,4-trimethoxyphenyl)oxirane;DTXSID201267027;116145-29-0

Suppliers and Price of 2-Methyl-3-(2,3,4-trimethoxyphenyl)oxirane

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Methyl-3-(2,3,4-trimethoxyphenyl)oxirane

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:224.10485899
Heavy Atom Count:16
Complexity:233

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1C(O1)C2=C(C(=C(C=C2)OC)OC)OC

Technology Process of 2-Methyl-3-(2,3,4-trimethoxyphenyl)oxirane

There total 2 articles about 2-Methyl-3-(2,3,4-trimethoxyphenyl)oxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2103-57-3
2,3,4-trimethoxybenzaldehyde

: 116145-29-0
1-(2',3',4'-trimethylphenyl)-1,2-epoxypropane

Guidance literature:: Multi-step reaction with 2 steps

1: 9.44 g / n-BuLi / tetrahydrofuran / -78 °C

2: 1.) N-bromosuccinimide; 2.) potassium carbonate / 1.) DME/H₂O, 0 deg C 75 min.; 2.) MeOH 30 min.

With N-Bromosuccinimide; n-butyllithium; potassium carbonate; In tetrahydrofuran;
DOI:10.1016/S0040-4020(01)87724-3

Reference yield:

: 81148-83-6
(E/Z)-2',3',4'-trimethoxy-1-propenylbenzene

: 116145-29-0
1-(2',3',4'-trimethylphenyl)-1,2-epoxypropane

Guidance literature:: With N-Bromosuccinimide; potassium carbonate; Multistep reaction; 1.) DME/H₂O, 0 deg C 75 min.; 2.) MeOH 30 min.;
DOI:10.1016/S0040-4020(01)87724-3

Reference yield:

: 116145-29-0
1-(2',3',4'-trimethylphenyl)-1,2-epoxypropane

: 116145-40-5
3-(5-Bromo-2,3,4-trimethoxy-phenyl)-propionic acid 2,2,2-trifluoro-ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 48 percent aq. HBr / methanol

2: N-bromosuccinimide, benzoyl peroxide / CCl₄ / Irradiation

3: 25 percent / Et₃N / 24 h / Ambient temperature

With N-Bromosuccinimide; Perbenzoic acid; hydrogen bromide; triethylamine; In methanol; tetrachloromethane;
DOI:10.1016/S0040-4020(01)87724-3