1,5-Benzothiazepine-2-carboxylic acid, 2,3-dihydro-4-(4-methylphenyl)-

Base Information

Chemical Name:1,5-Benzothiazepine-2-carboxylic acid, 2,3-dihydro-4-(4-methylphenyl)-
CAS No.:116274-70-5
Molecular Formula:C₁₇H₁₅NO₂S
Molecular Weight:297.378
Hs Code.:
DSSTox Substance ID:DTXSID001159684
Mol file:116274-70-5.mol

Synonyms:116274-70-5;1,5-Benzothiazepine-2-carboxylic acid, 2,3-dihydro-4-(4-methylphenyl)-;DTXSID001159684;AKOS000268184;2,3-Dihydro-4-(4-methylphenyl)-1,5-benzothiazepine-2-carboxylic acid

Suppliers and Price of 1,5-Benzothiazepine-2-carboxylic acid, 2,3-dihydro-4-(4-methylphenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,5-Benzothiazepine-2-carboxylic acid, 2,3-dihydro-4-(4-methylphenyl)-

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:297.08234989
Heavy Atom Count:21
Complexity:415

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=NC3=CC=CC=C3SC(C2)C(=O)O

Technology Process of 1,5-Benzothiazepine-2-carboxylic acid, 2,3-dihydro-4-(4-methylphenyl)-

There total 2 articles about 1,5-Benzothiazepine-2-carboxylic acid, 2,3-dihydro-4-(4-methylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 20972-36-5,35513-41-8,24849-45-4
4-(p-methylphenyl)-4-oxo-2-butenoic acid

: 137-07-5
2-amino-benzenethiol

: 116274-70-5
4-p-Tolyl-2,3-dihydro-benzo[b][1,4]thiazepine-2-carboxylic acid

Guidance literature:: With acetic acid; In ethanol; for 3h; Heating;

Reference yield:

: 108-88-3,15644-74-3,16713-13-6
toluene

: 116274-70-5
4-p-Tolyl-2,3-dihydro-benzo[b][1,4]thiazepine-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 50 percent / AlCl₃ / CS₂ / 5 °C

2: 65 percent / glacial acetic caid / ethanol / 3 h / Heating

With aluminium trichloride; acetic acid; In carbon disulfide; ethanol;