(-) ANATOXIN-A FUMARATE

Base Information

Chemical Name:(-) ANATOXIN-A FUMARATE
CAS No.:92142-32-0
Molecular Formula:C10H15 N O
Molecular Weight:165.2322
Hs Code.:
Mol file:92142-32-0.mol

Synonyms:Ethanone,1-(9-azabicyclo[4.2.1]non-2-en-2-yl)-, (1S)-; 9-Azabicyclo[4.2.1]nonane,ethanone deriv.; (-)-Anatoxin a

Suppliers and Price of (-) ANATOXIN-A FUMARATE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(-)-AnatoxinA
50mg
$ 10945.00

American Custom Chemicals Corporation
(-) ANATOXIN-A FUMARATE 95.00%
5MG
$ 499.03

Total 4 raw suppliers

Chemical Property of (-) ANATOXIN-A FUMARATE

Chemical Property:

Vapor Pressure:0.002mmHg at 25°C
Boiling Point:291°Cat760mmHg
Flash Point:124.7°C
PSA：29.10000
Density:1.037g/cm³
LogP:1.74500

Purity/Quality:

97% ^*data from raw suppliers

(-)-AnatoxinA ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses (-)-Anatoxin A is an effective agonist at low micromolar concentrations on acetylcholine receptor-ion channel activation and blockade.

Technology Process of (-) ANATOXIN-A FUMARATE

There total 38 articles about (-) ANATOXIN-A FUMARATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 108585-39-3,145375-60-6
2-acetyl-9-azabicyclo[4.2.1]non-2-ene-9-carboxylic acid methyl ester

: 64285-06-9,85514-42-7,92142-32-0
(+/-)-Anatoxin A

Guidance literature:: With trimethylsilyl iodide; In acetonitrile; at 0 - 20 ℃;
DOI:10.1021/jo0506682

Reference yield:

: 17342-08-4
(S)-Pyroglutaminol

: 64285-06-9,85514-42-7,92142-32-0
(+/-)-Anatoxin A

Guidance literature:: Multi-step reaction with 8 steps

1.1: 98 percent / Et₃N; DMAP / CH₂Cl₂ / 20 h / 20 °C

2.1: 51 percent / diethyl ether; tetrahydrofuran / 5 h / 20 °C

3.1: n-BuLi / tetrahydrofuran; hexane / 1 h / -78 °C

3.2: 91 percent / tetrahydrofuran; hexane / 2.5 h / -78 - 0 °C

4.1: NaBH₄; aq. H₂SO₄ / 6.5 h / -20 °C

4.2: aq. H₂SO₄ / 1.5 h / 0 - 2 °C

5.1: O₃ / CH₂Cl₂ / 0.33 h / -78 °C

5.2: 1.17 g / PPh₃ / CH₂Cl₂ / -78 - 20 °C

6.1: 88 percent / LiCl; i-Pr₂NEt / acetonitrile / 6 h / 20 °C

7.1: HCl gas / methanol / -50 - 20 °C

7.2: 51 percent / DBU / toluene / 6.5 h / Heating

8.1: 65 percent / TMSI / acetonitrile / 0 - 20 °C

With hydrogenchloride; dmap; sodium tetrahydroborate; n-butyllithium; trimethylsilyl iodide; sulfuric acid; ozone; triethylamine; N-ethyl-N,N-diisopropylamine; lithium chloride; In tetrahydrofuran; methanol; diethyl ether; hexane; dichloromethane; acetonitrile; 6.1: Horner-Wadsworth-Emmons reaction;
DOI:10.1021/jo0506682