INOSINE-3',5'-CYCLIC PHOSPHATE

Base Information

• Chemical Name: INOSINE-3',5'-CYCLIC PHOSPHATE
• CAS No.: 3545-76-4
• Molecular Formula: C10H11 N4 O7 P
• Molecular Weight: 330.194
• Mol file: 3545-76-4.mol

Synonyms:Inosine,cyclic 3',5'-phosphate (7CI); 4H-Furo[3,2-d]-1,3,2-dioxaphosphorin, inosinederiv.; 3',5'-IMP; Cyclic 3',5'-IMP; Cyclic 3',5'-inosinic acid; Cyclic IMP;Cyclic inosine 3',5'-monophosphate; Cyclic inosine monophosphate; Inosine3',5'-cyclic monophosphate; Inosine 3',5'-monophosphate; Inosinecyclophosphate; cIMP

Chemical Property of INOSINE-3',5'-CYCLIC PHOSPHATE

Chemical Property:

• Boiling Point: 751.8°Cat760mmHg
• Flash Point: 408.5°C
• PSA: 158.86000
• Density: 2.47g/cm³
• LogP: -0.69400

Purity/Quality:

97% ^*data from raw suppliers

Inosine-3?-5?-cyclic-monophosphatefreeacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of INOSINE-3',5'-CYCLIC PHOSPHATE

There total 7 articles about INOSINE-3',5'-CYCLIC PHOSPHATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

cAMP (60-92-4) → inosine 3′,5′-cyclic monophosphate (3545-76-4)

Guidance literature:

With phosphate buffer; at 25 ℃; for 5h; AMP deaminase from Aspergillus sp.;

DOI:10.1021/jo00103a010

Reference yield:

C10H11Cl2N4O6P → inosine 3′,5′-cyclic monophosphate (3545-76-4)

Guidance literature:

With potassium hydroxide; In water; acetonitrile; at 0 ℃; Yield given;

DOI:10.1055/s-1989-27150

Reference yield:

Inosine (58-63-9) → inosine 3′,5′-cyclic monophosphate (3545-76-4)

Guidance literature:

Multi-step reaction with 2 steps

1: POCl₃ / various solvent(s) / 3 h / 0 °C

2: 0.08 M KOH / acetonitrile; H₂O / 0 °C

With potassium hydroxide; trichlorophosphate; In water; acetonitrile;

DOI:10.1055/s-1989-27150

upstream raw materials:

cAMP

Inosine

Refernces

• 1、 Genieser,Butt,Bottin,Dostmann,Jastorff. "Synthesis of the 3',5'-cyclic phosphates from unprotected nucleosides". . p. 53 - 54. Retrieved 2007/10/02.