1,2-Ethanediol, 1-(3,4,5-trimethoxyphenyl)-

Base Information

Chemical Name:1,2-Ethanediol, 1-(3,4,5-trimethoxyphenyl)-
CAS No.:116673-46-2
Molecular Formula:C11H16O5
Molecular Weight:228.245
Hs Code.:
DSSTox Substance ID:DTXSID50446111
Nikkaji Number:J2.892.245K
ChEMBL ID:CHEMBL2203979
Mol file:116673-46-2.mol

Synonyms:1-(3,4,5-trimethoxyphenyl)ethane-1,2-diol;1,2-Ethanediol, 1-(3,4,5-trimethoxyphenyl)-;116673-46-2;CHEMBL2203979;DTXSID50446111;AKOS021030907;1-(3,4,5-Trimethoxyphenyl)-1,2-ethanediol;EN300-1855819

Suppliers and Price of 1,2-Ethanediol, 1-(3,4,5-trimethoxyphenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1,2-Ethanediol, 1-(3,4,5-trimethoxyphenyl)-

Chemical Property:

XLogP3:-0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:228.09977361
Heavy Atom Count:16
Complexity:185

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=CC(=C1OC)OC)C(CO)O

Technology Process of 1,2-Ethanediol, 1-(3,4,5-trimethoxyphenyl)-

There total 4 articles about 1,2-Ethanediol, 1-(3,4,5-trimethoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13400-02-7
3,4,5-trimethoxy styrene

: 116673-46-2
1-(3,4,5-trimethoxyphenyl)-1,2-dihydroxyethane

Guidance literature:: 3,4,5-trimethoxy styrene; With osmium(VIII) oxide; N-morpholine-N-oxide; In water; acetone; tert-butyl alcohol; at 20 ℃; for 71h;

With sodium metabisulfite; In water; acetone; tert-butyl alcohol; for 1h; Further stages.;
DOI:10.1021/jm010231w

Reference yield:

: 13400-02-7
3,4,5-trimethoxy styrene

: 1373919-38-0
2,3,4-trimethoxy-6-vinylbenzonitrile

: 1373919-64-2
(R)-3-(hydroxymethyl)-5,6,7-trimethoxyisobenzofuran-1(3H)-one

: 116673-46-2
1-(3,4,5-trimethoxyphenyl)-1,2-dihydroxyethane

Guidance literature:: With AD-mix β; In tetrahydrofuran; water; tert-butyl alcohol; at 25 ℃; for 3h;
DOI:10.1039/c2ob25409c

Reference yield:

: 86-81-7
3,4,5-trimethoxy-benzaldehyde

: 116673-46-2
1-(3,4,5-trimethoxyphenyl)-1,2-dihydroxyethane

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butylate / toluene

2: osmium(VIII) oxide; 4-methylmorpholine N-oxide / tetrahydrofuran / 55 °C

With osmium(VIII) oxide; potassium tert-butylate; 4-methylmorpholine N-oxide; In tetrahydrofuran; toluene;
DOI:10.1016/j.bmcl.2012.09.096