N-benzyl-5-bromofuran-2-carboxamide

Base Information

Chemical Name:N-benzyl-5-bromofuran-2-carboxamide
CAS No.:117845-23-5
Molecular Formula:C12H10BrNO2
Molecular Weight:280.121
Hs Code.:
DSSTox Substance ID:DTXSID70354047
Wikidata:Q82131975
ChEMBL ID:CHEMBL1433202
Mol file:117845-23-5.mol

Synonyms:N-benzyl-5-bromofuran-2-carboxamide;117845-23-5;N-benzyl-5-bromo-2-furamide;KUC100027;MLS000518278;Cambridge id 5245842;CBDivE_008452;SCHEMBL430687;CHEMBL1433202;DTXSID70354047;HMS2205D19;HMS3339B15;KUC100027N;MFCD00454467;STK416125;AKOS001326536;SB61056;BS-36854;SMR000129107;CS-0270016;AB00076582-01;SR-01000200692;SR-01000200692-1;Z27749618

Suppliers and Price of N-benzyl-5-bromofuran-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of N-benzyl-5-bromofuran-2-carboxamide

Chemical Property:

Vapor Pressure:5.6E-07mmHg at 25°C
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:278.98949
Heavy Atom Count:16
Complexity:241

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CNC(=O)C2=CC=C(O2)Br

Technology Process of N-benzyl-5-bromofuran-2-carboxamide

There total 2 articles about N-benzyl-5-bromofuran-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 26726-16-9
5-bromofuran-2-carbonyl chloride

: 100-46-9
benzylamine

: 117845-23-5
5-bromofuran-2-carboxylic acid benzylamide

Guidance literature:: In benzene; for 0.5h; Heating;

Reference yield:

: 585-70-6
5-bromo-furan-2-carboxylic acid

: 117845-23-5
5-bromofuran-2-carboxylic acid benzylamide

Guidance literature:: Multi-step reaction with 2 steps

1: (COCl)2 / CH₂Cl₂; dimethylformamide / 1.5 h / 0 - 20 °C

2: 15 g / Et₃N / tetrahydrofuran / 1 h / 0 - 20 °C

With oxalyl dichloride; triethylamine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ol035233k

Reference yield: 99.0%

: 117845-23-5
5-bromofuran-2-carboxylic acid benzylamide

: 106-95-6
allyl bromide

: 583052-92-0
5-bromofuran-2-carboxylic acid N-allyl-N-benzylamide

Guidance literature:: 5-bromofuran-2-carboxylic acid benzylamide; With sodium hydroxide; (n-Bu₄)HSO₄; potassium carbonate; In benzene; at 20 ℃; for 1h;

allyl bromide; In benzene; at 20 ℃; for 22h;
DOI:10.1021/ol035233k