1-(4-(Benzyloxy)-6-hydroxy-7-methoxybenzofuran-5-yl)ethanone

Base Information

Chemical Name:1-(4-(Benzyloxy)-6-hydroxy-7-methoxybenzofuran-5-yl)ethanone
CAS No.:119104-31-3
Molecular Formula:C18H16O5
Molecular Weight:312.322
Hs Code.:
ChEMBL ID:CHEMBL203798
DSSTox Substance ID:DTXSID20468466
Wikidata:Q82295667

Synonyms:119104-31-3;CHEMBL203798;1-(4-(benzyloxy)-6-hydroxy-7-methoxybenzofuran-5-yl)ethanone;SCHEMBL1344800;DTXSID20468466;1-(6-hydroxy-7-methoxy-4-phenylmethoxy-1-benzofuran-5-yl)ethanone;BDBM50182630

Suppliers and Price of 1-(4-(Benzyloxy)-6-hydroxy-7-methoxybenzofuran-5-yl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-(4-(Benzyloxy)-6-hydroxy-7-methoxybenzofuran-5-yl)ethanone

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:312.09977361
Heavy Atom Count:23
Complexity:406

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=C(C2=C(C(=C1O)OC)OC=C2)OCC3=CC=CC=C3

Technology Process of 1-(4-(Benzyloxy)-6-hydroxy-7-methoxybenzofuran-5-yl)ethanone

There total 6 articles about 1-(4-(Benzyloxy)-6-hydroxy-7-methoxybenzofuran-5-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 115249-37-1
5-benzyloxykhellin

: 119104-31-3
1-(4-benzyloxy-6-hydroxy-7-methoxy-benzofuran-5-yl)-ethanone

Guidance literature:: With sodium hydroxide; In ethanol; at 70 ℃; for 3h;
DOI:10.1021/jm050839v

Reference yield: 62.0%

: 119104-31-3
1-(4-benzyloxy-6-hydroxy-7-methoxy-benzofuran-5-yl)-ethanone

Guidance literature:

Reference yield:

: 2159-83-3
4,9-Dihydroxy-7-methyl-5H-furo<3,2-g><1>benzopyran-5-one

: 119104-31-3
1-(4-benzyloxy-6-hydroxy-7-methoxy-benzofuran-5-yl)-ethanone

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / K₂CO₃ / acetonitrile / 1.5 h / 80 °C

2: 82 percent / cesium carbonate / dimethylformamide / 20 °C

3: 75 percent / aq. NaOH / ethanol / 3 h / 70 °C

With sodium hydroxide; potassium carbonate; caesium carbonate; In ethanol; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jm050839v