5-[(2,4-Dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-amine

Base Information

Chemical Name:5-[(2,4-Dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-amine
CAS No.:119869-04-4
Molecular Formula:C11H13N3OS
Molecular Weight:235.31
Hs Code.:2934999090
DSSTox Substance ID:DTXSID90350662
Wikidata:Q82126720
Mol file:119869-04-4.mol

Synonyms:119869-04-4;5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-amine;5-((2,4-Dimethylphenoxy)methyl)-1,3,4-thiadiazol-2-amine;Oprea1_242397;Oprea1_727795;DTXSID90350662;MFCD01346792;STK711807;AKOS001619412;BS-35655;AG-205/37199066;SR-01000436279;SR-01000436279-1

Suppliers and Price of 5-[(2,4-Dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-[(2,4-Dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-amine
100mg
$ 60.00

ChemBridge Corporation
5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-amine 95%
5 g
$ 460.00

ChemBridge Corporation
5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-amine 95%
1 g
$ 140.00

American Custom Chemicals Corporation
5-[(2,4-DIMETHYLPHENOXY)METHYL]-1,3,4-THIADIAZOL-2-AMINE 95.00%
5G
$ 1334.03

American Custom Chemicals Corporation
5-[(2,4-DIMETHYLPHENOXY)METHYL]-1,3,4-THIADIAZOL-2-AMINE 95.00%
1G
$ 764.03

Total 2 raw suppliers

Chemical Property of 5-[(2,4-Dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-amine

Chemical Property:

Vapor Pressure:1.88E-07mmHg at 25°C
Boiling Point:425.7oC at 760 mmHg
Flash Point:211.2oC
PSA：89.27000
Density:1.272g/cm3
LogP:2.89730
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:235.07793322
Heavy Atom Count:16
Complexity:229

Purity/Quality:: 5-[(2,4-Dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)OCC2=NN=C(S2)N)C

Technology Process of 5-[(2,4-Dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-amine

There total 6 articles about 5-[(2,4-Dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: C₁₁H₁₅N₃O₂S

: 119869-04-4
5-(2,4-Dimethyl-phenoxymethyl)-[1,3,4]thiadiazol-2-ylamine

Guidance literature:: With phosphoric acid; at 120 ℃; for 2h;
DOI:10.1016/j.bmc.2010.11.034

Reference yield:

: 13334-49-1
2-(2,4-dimethylphenoxy)acetic acid

: 79-19-6
thiosemicarbazide

: 119869-04-4
5-(2,4-Dimethyl-phenoxymethyl)-[1,3,4]thiadiazol-2-ylamine

Guidance literature:: 2-(2,4-dimethylphenoxy)acetic acid; thiosemicarbazide; With trichlorophosphate; at 75 ℃; for 0.5h;

In water; for 4h; Reflux;
DOI:10.1016/j.bioorg.2015.03.001

Reference yield:

: 176450-08-1
ethyl 2-(2,4-dimethylphenoxy)acetate

: 119869-04-4
5-(2,4-Dimethyl-phenoxymethyl)-[1,3,4]thiadiazol-2-ylamine

Guidance literature:: Multi-step reaction with 3 steps

1: hydrazine hydrate / methanol / 1 h / 20 °C

2: ethanol / 4 h / Reflux

3: phosphoric acid / 2 h / 120 °C

With ethanol; phosphoric acid; hydrazine hydrate; In methanol;
DOI:10.1016/j.bmc.2010.11.034