tert-Butyl (5-(benzyloxy)-2-bromophenyl)carbamate

Base Information

Chemical Name:tert-Butyl (5-(benzyloxy)-2-bromophenyl)carbamate
CAS No.:119879-92-4
Molecular Formula:C18H20BrNO3
Molecular Weight:378.266
Hs Code.:2924299090
DSSTox Substance ID:DTXSID00558450
Wikidata:Q72510972
Mol file:119879-92-4.mol

Synonyms:119879-92-4;tert-Butyl (5-(benzyloxy)-2-bromophenyl)carbamate;N-[2-BROMO-5-(PHENYLMETHOXY)PHENYL]CARBAMIC ACID TERT-BUTYL ESTER;tert-butyl N-(2-bromo-5-phenylmethoxyphenyl)carbamate;tert-Butyl [5-(benzyloxy)-2-bromophenyl]carbamate;DTXSID00558450;MFCD16658925;AKOS015902010;F12032;tert-Butyl(5-(benzyloxy)-2-bromophenyl)carbamate

Suppliers and Price of tert-Butyl (5-(benzyloxy)-2-bromophenyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl(5-(benzyloxy)-2-bromophenyl)carbamate 95+%
1g
$ 371.00

Alichem
tert-Butyl(5-(benzyloxy)-2-bromophenyl)carbamate
1g
$ 400.00

Total 13 raw suppliers

Chemical Property of tert-Butyl (5-(benzyloxy)-2-bromophenyl)carbamate

Chemical Property:

Melting Point:84-86oC
PSA：51.05000
Density:1.354
LogP:5.38870
Storage Temp.:2-8°C
XLogP3:4.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:377.06266
Heavy Atom Count:23
Complexity:377

Purity/Quality:

99% ^*data from raw suppliers

tert-Butyl(5-(benzyloxy)-2-bromophenyl)carbamate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=C(C=CC(=C1)OCC2=CC=CC=C2)Br

Technology Process of tert-Butyl (5-(benzyloxy)-2-bromophenyl)carbamate

There total 4 articles about tert-Butyl (5-(benzyloxy)-2-bromophenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 119879-90-2
5-(Benzyloxy)-2-bromophenylamine

: 119879-92-4
5-(benzyloxy)-2-bromo-N-((tert-butyloxy)carbonyl)aniline

Guidance literature:: In 1,4-dioxane; at 105 ℃; for 10h;
DOI:10.1021/jo00267a004

Reference yield:

: 1484-26-0
3-(benzyloxy)aniline

: 119879-92-4
5-(benzyloxy)-2-bromo-N-((tert-butyloxy)carbonyl)aniline

Guidance literature:: Multi-step reaction with 2 steps

1: 42 percent / N-bromosuccinimide, H₂SO₄ / tetrahydrofuran / 10 h / -78 °C

2: 85 percent / dioxane / 10 h / 105 °C

With N-Bromosuccinimide; sulfuric acid; In tetrahydrofuran; 1,4-dioxane;
DOI:10.1021/jo00267a004