3-Hydroxy-2-phenylpropyl carbamate

Base Information

Chemical Name:3-Hydroxy-2-phenylpropyl carbamate
CAS No.:25451-53-0
Molecular Formula:C10H13 N O3
Molecular Weight:195.218
Hs Code.:
UNII:I38CB53794
DSSTox Substance ID:DTXSID00948337
Nikkaji Number:J440.350I
Wikidata:Q27149627
ChEMBL ID:CHEMBL2259639
Mol file:25451-53-0.mol

Synonyms:2-phenyl-1,3-propanediol monocarbamate;SCH 54388

Suppliers and Price of 3-Hydroxy-2-phenylpropyl carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Hydroxy-2-phenylpropylCarbamate
100mg
$ 1940.00

Medical Isotopes, Inc.
Hydroxy-2-phenylpropylCarbamate
100 mg
$ 2675.00

Total 8 raw suppliers

Chemical Property of 3-Hydroxy-2-phenylpropyl carbamate

Chemical Property:

Vapor Pressure:1.24E-07mmHg at 25°C
Melting Point:72-74 °C
Boiling Point:415.1°Cat760mmHg
PKA:13.33±0.50(Predicted)
Flash Point:204.8°C
PSA：73.54000
Density:1.214g/cm³
LogP:1.37160
Storage Temp.:-20°C Freezer
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:195.08954328
Heavy Atom Count:14
Complexity:178

Purity/Quality:

97% ^*data from raw suppliers

Hydroxy-2-phenylpropylCarbamate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(CO)COC(=O)N
Uses Hydroxy-2-phenylpropyl Carbamate is an impurity in the synthesis of Felbamate (F231000), an antiepileptic, structurally similar to meprobamate.

Technology Process of 3-Hydroxy-2-phenylpropyl carbamate

There total 10 articles about 3-Hydroxy-2-phenylpropyl carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 109482-33-9
2-phenyl-3-methoxy-propanol carbamate

: 25451-53-0
2-phenyl-1,3-propanediol monocarbamate

Guidance literature:: With trichloromethyl silane; sodium iodide; In acetonitrile; for 24h; Ambient temperature;
DOI:10.1016/S0040-4020(01)88100-X

Reference yield: 95.0%

: 3-hydroxy-2-phenylpropyl 4-methoxybenzylcarbamate

: 25451-53-0
2-phenyl-1,3-propanediol monocarbamate

Guidance literature:: With ammonium cerium (IV) nitrate; In water; acetonitrile; at 0 - 20 ℃; for 4h;
DOI:10.1002/adsc.201500895

Reference yield: 78.0%

: 1570-95-2
2-phenylpropane-1, 3-diol

: 530-62-1
1,1'-carbonyldiimidazole

: 211506-14-8
2-fluoro-2-phenyl-1,3-propanediol

: 726-99-8
Fluorofelbamate

: 288302-42-1
Fluoro monocarbamate felbamate

: 25451-53-0
2-phenyl-1,3-propanediol monocarbamate

: 25451-15-4
felbamate

Guidance literature:: 2-phenylpropane-1, 3-diol; 1,1'-carbonyldiimidazole; 2-fluoro-2-phenyl-1,3-propanediol; In tetrahydrofuran;

With ammonium carbonate; In tetrahydrofuran; for 38 - 72h; Molecular sieve;