Cerium(III) nitrate hexahydrate

Base Information

• Chemical Name: Cerium(III) nitrate hexahydrate
• CAS No.: 10294-41-4
• Molecular Formula: Ce(NO3)3^.6(H2O)
• Molecular Weight: 434.22
• Hs Code.: 28461090
• European Community (EC) Number: 600-370-9
• UNII: FL1R38JEBB
• DSSTox Substance ID: DTXSID701015566
• Wikidata: Q3877360
• Mol file: 10294-41-4.mol

Synonyms:Cerium(III) nitrate hexahydrate;10294-41-4;cerium nitrate hexahydrate;Cerous nitrate hexahydrate;Cerium trinitrate hexahydrate;cerium (III) nitrate hexahydrate;cerium(3+);trinitrate;hexahydrate;MFCD00149631;FL1R38JEBB;Nitric acid, cerium(3+) salt, hexahydrate;Cerium(III) nitrate hexahydrate, REacton?;UNII-FL1R38JEBB;Cerium nitrate, hexahydrate;TRANS-STYRYLACETICACID;CERIUM(III) NITRATE, HEXAHYDRATE (1:3:6);DTXSID701015566;MFCD09953662;AKOS025243957;Cerium(III) nitrate hexahydrate, p.a., 99.5%;Q3877360;Cerium(III) nitrate hexahydrate, 99% trace metals basis;Cerium(III) nitrate hexahydrate, 99.99% trace metals basis;Cerium(III) nitrate hexahydrate, 99.999% trace metals basis

Chemical Property of Cerium(III) nitrate hexahydrate

Chemical Property:

• Appearance/Colour: red-tinted or colourless crystals
• Melting Point: 96 °C
• Boiling Point: 200 °C
• PSA: 262.02000
• Density: 4.37 g/cm³
• LogP: 0.46650
• Storage Temp.: 0-6°C
• Sensitive.: Hygroscopic
• Solubility.: 1754g/l
• Water Solubility.: Soluble in water, alcohol and acetone.
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 15
• Rotatable Bond Count: 0
• Exact Mass: 433.93229
• Heavy Atom Count: 19
• Complexity: 18.8

Purity/Quality:

99.99% ^*data from raw suppliers

Cerium(III) nitrate hexahydrate (99.9%-Ce) (REO) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi; O
• Hazard Codes: O,Xi,N
• Statements: 8-41-50/53-52/53-36/38
• Safety Statements: 17-26-39-61-60

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: [N+](=O)([O-])[O-].[N+](=O)([O-])[O-].[N+](=O)([O-])[O-].O.O.O.O.O.O.[Ce+3]
• Uses: Cerium nitrate hexahydrate, is the optimum materials for manufacturing Cerium-doped catalyst, and also applied in making auto gauze covering. Cerium(III) nitrate hexahydrate is used in the separation of cerium from other rare earths. It plays an important role as a catalyst for hydrolysis of phosphoric acid esters.

Refernces

Synthesis of dihydropyrimidine α,μ3-diketobutanoic acid derivatives targeting HIV integrase

10.1016/j.ejmech.2015.09.015

This study focused on the synthesis and antiviral evaluation of dihydropyrimidone and thiopyrimidine derivatives that target HIV integrase, a crucial enzyme in the HIV replication cycle. A series of compounds bearing an aromatic α,γ-diketobutyric acid moiety were synthesized using the Biginelli multicomponent reaction as a key step. The synthesized compounds were evaluated for their ability to inhibit HIV-1 integrase (IN) strand transfer (ST) activity in vitro, with the most active compounds showing nanomolar inhibitory activity. To further understand the interaction mode within the active site of IN, molecular docking analysis was performed using the X-ray crystal structure of IN. The experiments involved the use of various reagents, catalysts, and solvents, and the synthesized compounds were analyzed using techniques such as thin layer chromatography (TLC), column chromatography, NMR spectroscopy, and high-resolution mass spectrometry. Cerium(III) nitrate hexahydrate (Ce(NO3)3.6H2O), lithium hexamethyldisilazide (LiHMDS), and other reagents were used. Biological evaluation included evaluation of enzymatic activity and evaluation of antiviral activity in cellular models. Molecular modeling studies were performed using the Schrodinger Molecular Modeling Suite, and docking simulations were performed to predict the binding mode of the compounds within the HIV integrase active site.