Ethyl 4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate

Base Information Edit

Chemical Name:Ethyl 4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate
CAS No.:391-02-6
Molecular Formula:C13H10 F3 N O3
Molecular Weight:285.223
Hs Code.:2933499090
European Community (EC) Number:206-871-5
NSC Number:96992
DSSTox Substance ID:DTXSID50192343
Nikkaji Number:J213.618J
Wikidata:Q83064998
ChEMBL ID:CHEMBL2031104
Mol file:391-02-6.mol

Synonyms:391-02-6;ethyl 4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate;Ethyl 4-oxo-7-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate;71083-04-0;Ethyl 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylate;ethyl 4-oxo-7-(trifluoromethyl)-1H-quinoline-3-carboxylate;EINECS 206-871-5;ethyl 4-hydroxy-7-(trifluoromethyl)-3-quinolinecarboxylate;ETHYL4-HYDROXY-7-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE;NSC96992;BIDD:GT0531;SCHEMBL430575;CHEMBL2031104;DTXSID50192343;MFCD00006769;MFCD01080777;NSC 96992;NSC-96992;STK849366;AKOS000119871;AKOS000520751;SB69001;SB69057;LS-04436;CS-0206801;CS-0368607;FT-0632074;EN300-17357;A866497;AG-690/37012007;SR-01000432011;SR-01000432011-1;Z56922121;ethyl 4-hydroxy-7-trifluoromethylquinoline-3-carboxylate;Ethyl-4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylate;ethyl-4-hydroxy-7-trifluoro-methyl-3-quinolinecarboxylate;Ethyl 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylate, 95%;4-Hydroxy-7-trifluoromethyl-quinoline-3-carboxylic acid ethyl ester;ethyl 4-oxo-7-(trifluoromethyl)-1,4-dihydro-3-quinolinecarboxylate;3-Quinolinecarboxylic acid, 4-hydroxy-7-(trifluoromethyl)-, ethyl ester

Suppliers and Price of Ethyl 4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Ethyl 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylate 95%
5g
$ 188.00

Crysdot
Ethyl4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate 95+%
10g
$ 324.00

Chemenu
Ethyl4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate 95%
10g
$ 490.00

Chemenu
Ethyl4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate 95%
5g
$ 330.00

American Custom Chemicals Corporation
ETHYL 4-HYDROXY-7-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE 95.00%
5G
$ 1005.43

American Custom Chemicals Corporation
ETHYL 4-HYDROXY-7-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE 95.00%
2.5G
$ 852.21

American Custom Chemicals Corporation
ETHYL 4-HYDROXY-7-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE 95.00%
1G
$ 648.81

Alichem
Ethyl4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate
25g
$ 1749.30

Alichem
Ethyl4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate
10g
$ 1015.05

Alichem
Ethyl4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate
5g
$ 602.41

Total 22 raw suppliers

Chemical Property of Ethyl 4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate Edit

Chemical Property:

Vapor Pressure:4.89E-05mmHg at 25°C
Melting Point:>300 °C(lit.)
Boiling Point:348.9°Cat760mmHg
Flash Point:164.8°C
PSA：59.42000
Density:1.373g/cm³
LogP:3.13590
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:285.06127767
Heavy Atom Count:20
Complexity:445

Purity/Quality:

98%min ^*data from raw suppliers

Ethyl 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylate 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCOC(=O)C1=CNC2=C(C1=O)C=CC(=C2)C(F)(F)F
Uses Ethyl 4-Hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate (CAS# 391-02-6) can be used as a potent antimicrobial agent. It can also be prepared as TRPV1 antagonist for therapy.

Technology Process of Ethyl 4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate

There total 17 articles about Ethyl 4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%