Germanamine, 1-chloro-1,1-diphenyl-N-(2,4,6-trimethylphenyl)-

Base Information

• Chemical Name: Germanamine, 1-chloro-1,1-diphenyl-N-(2,4,6-trimethylphenyl)-
• CAS No.: 122422-42-8
• Molecular Formula: C21H22ClGeN
• Molecular Weight: 396.455
• Mol file: 122422-42-8.mol

Synonyms:

Chemical Property of Germanamine, 1-chloro-1,1-diphenyl-N-(2,4,6-trimethylphenyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Germanamine, 1-chloro-1,1-diphenyl-N-(2,4,6-trimethylphenyl)-

There total 2 articles about Germanamine, 1-chloro-1,1-diphenyl-N-(2,4,6-trimethylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2,4,6-trimethylaniline (88-05-1) + dichlorodiphenylgermane (1613-66-7) → (C6H5)2ClGeNHC6H2(CH3)3 (122422-42-8)

Guidance literature:

With triethylamine; In benzene; byproducts: Et3N*HCl; inert atmosphere (Ar or N2); 20°C, 17 h; filtn., pptn. on concn.; elem. anal.;

DOI:10.1016/0022-328X(88)87072-4

Reference yield: 35.0%

lithium 2,4,6-trimethylaniline (65768-38-9) + dichlorodiphenylgermane (1613-66-7) → (C6H5)2ClGeNHC6H2(CH3)3 (122422-42-8)

Guidance literature:

In diethyl ether; benzene; byproducts: LiCl; dissolving C6H2(CH3)3NHLi in THF; addn. to (C6H5)GeCl2 (3.7 mmol) in C6H6/ether; storing for 17 h at ambient temp.;; removing LiCl, evapg. solvent; recrystn. from pentane at -30°C;;

Reference yield: 67.0%

(C6H5)2ClGeNHC6H2(CH3)3 (122422-42-8) + 3,5-di-tert-butyl-o-benzoquinone (3383-21-9) → 2,2-diphenyl(6,8-di-t-butyl)-4,5-benzo-2-germa-1,3-dioxolane (110577-23-6) + ditertiobutyl-2,4 (trimethyl-2,4,6 phenylimino)-6 cyclohexadiene-2,4 one-1 (112079-83-1) + 2,4,6-trimethylaniline (88-05-1)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In benzene-d6; byproducts: DBU*HCl; inert atmosphere (Ar or N2); 20°C, 17 h; (1)H-NMR; evapn., pentane addn., filtn.;

DOI:10.1016/0022-328X(88)87072-4

upstream raw materials:

2,4,6-trimethylaniline

dichlorodiphenylgermane

lithium 2,4,6-trimethylaniline

Downstream raw materials:

2,2-diphenyl(6,8-di-t-butyl)-4,5-benzo-2-germa-1,3-dioxolane

ditertiobutyl-2,4 (trimethyl-2,4,6 phenylimino)-6 cyclohexadiene-2,4 one-1

2,4,6-trimethylaniline

(C₆H₅)2Ge(NHC₆H₂(CH₃)3)2